Reaction Details Report a problem with these data
Target
HTH-type transcriptional regulator EthR
Ligand
BDBM228830
Substrate
n/a
Meas. Tech.
Isothermal Titration Calorimetry (ITC)
Kd
1.1e+4±n/a nM
Citation
Nikiforov, PO; Blaszczyk, M; Surade, S; Boshoff, HI; Sajid, A; Delorme, V; Deboosere, N; Brodin, P; Baulard, AR; Barry, CE; Blundell, TL; Abell, C Fragment-Sized EthR Inhibitors Exhibit Exceptionally Strong Ethionamide Boosting Effect in Whole-Cell Mycobacterium tuberculosis Assays. ACS Chem Biol 12:1390-1396 (2017) [PubMed] Article
More Info.:
Target
Name:
HTH-type transcriptional regulator EthR
Synonyms:
ETHR_MYCTU | HTH-type transcriptional regulator EthR | Transcriptional repressor EthR (EthR) | etaR | ethR
Type:
Protein
Mol. Mass.:
23751.94
Organism:
Mycobacterium tuberculosis
Description:
P9WMC1
Residue:
216
Sequence:
MTTSAASQASLPRGRRTARPSGDDRELAILATAENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTLAENPADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR