Reaction Details
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Report a problem with these dataTarget
Glutathione S-transferase P
Ligand
BDBM4078
Substrate
n/a
Meas. Tech.
GST Assay
IC50
5.0e+4±n/a nM
Citation
Mangoyi, R; Hayeshi, R; Ngadjui, B; Ngandeu, F; Bezabih, M; Abegaz, B; Razafimahefa, S; Rasoanaivo, P; Mukanganyama, S Glutathione transferase from Plasmodium falciparum--interaction with malagashanine and selected plant natural products. J Enzyme Inhib Med Chem 25:854-62 (2010) [PubMed] Article More Info.:
Target
Name:
Glutathione S-transferase P
Synonyms:
GST class-pi | Glutathione S-transferase P | Glutathione S-transferase (GST) | GSTP1-1 | Glutathione S-transferase | GSTP1_HUMAN | GSTP1 | FAEES3 | GST3 | Glutathione S-transferase Pi | Glutathione transferase (GST)
Type:
Enzyme
Mol. Mass.:
23353.53
Organism:
Human
Description:
P09211
Residue:
210
Sequence:
MPPYTVVYFPVRGRCAALRMLLADQGQSWKEEVVTVETWQEGSLKASCLYGQLPKFQDGDLTLYQSNTILRHLGRTLGLYGKDQQEAALVDMVNDGVEDLRCKYISLIYTNYEAGKDDYVKALPGQLKPFETLLSQNQGGKTFIVGDQISFADYNLLDLLLIHEVLAPGCLDAFPLLSAYVGRLSARPKLKAFLASPEYVNLPINGNGKQ
Inhibitor
Name:
BDBM4078
Synonyms:
Elagic Acid | CHEMBL6246 | 6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0^{4,16}.0^{11,15}]hexadeca-1(14),4(16),5,7,11(15),12-hexaene-3,10-dione | SMR000058244 | MLS000069632 | ELLAGIC ACID | cid_5281855 | Ellagic acid dihydrate | Ellagic acid (18)
Type:
Small organic molecule
Emp. Form.:
C14H6O8
Mol. Mass.:
302.01
SMILES:
c1c2c-3c(c(c1O)O)OC(=O)c4c3c(c(c(c4)O)O)OC2=O
Structure:
