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Target
Carbonic anhydrase 6
Ligand
BDBM45795
Substrate
n/a
Meas. Tech.
Esterase Activity Assay
IC50
42390±n/a nM
Citation
 Alp, C; Özsoy, Å¿; Alp, NA; Erdem, D; Gültekin, MS; Küfrevioglu, ÿİ; Sentürk, M; Supuran, CT Sulfapyridine-like benzenesulfonamide derivatives as inhibitors of carbonic anhydrase isoenzymes I, II and VI. J Enzyme Inhib Med Chem 27:818-24 (2012) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 6
Synonyms:
CA-VI | CA6 | CAH6_HUMAN | Carbonate dehydratase VI | Carbonic Anhydrase VI | Carbonic anhydrase | Carbonic anhydrase 6 | Carbonic anhydrase 6 (CA VI) | Carbonic anhydrase 6 (CA-VI) | Carbonic anhydrase VI (CA VI) | Salivary carbonic anhydrase | Secreted carbonic anhydrase
Type:
Enzyme
Mol. Mass.:
35371.40
Organism:
Homo sapiens (Human)
Description:
P23280
Residue:
308
Sequence:
MRALVLLLSLFLLGGQAQHVSDWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMVNNGHTVQISLPSTMRMTVADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIHIVHYNSKYKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLTGLDVQDMLPRNLQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLENSLLDHRNKTIHNDYRRTQPLNHRVVESNFPNQEYTLGSEFQFYLHKIEEILDYLRRALN
  
Inhibitor
Name:
BDBM45795
Synonyms:
4-methyl-N-(2-naphthalenyl)benzenesulfonamide | 4-methyl-N-(2-naphthyl)benzenesulfonamide | 4-methyl-N-naphthalen-2-yl-benzenesulfonamide | 4-methyl-N-naphthalen-2-ylbenzenesulfonamide | CA inhibitor, 3 | MLS-0090805.0001 | cid_224144
Type:
Small organic molecule
Emp. Form.:
C17H15NO2S
Mol. Mass.:
297.371
SMILES:
Cc1ccc(cc1)S(=O)(=O)Nc1ccc2ccccc2c1
Structure:
Search PDB for entries with ligand similarity: