Reaction Details Report a problem with these data
Target
Carbonic anhydrase 3
Ligand
BDBM23416
Substrate
n/a
Meas. Tech.
Esterase Activity Assay
pH
7.4000±n/a
Ki
9.71e+3±n/a nM
Comments
extracted
Citation
 Koz, ÿ; Ekinci, D; Perrone, A; Piacente, S; Alankus-Çaliskan, ÿ; Bedir, E; Supuran, CT Analysis of saponins and phenolic compounds as inhibitors of a-carbonic anhydrase isoenzymes. J Enzyme Inhib Med Chem 28:412-7 (2013) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 3
Synonyms:
CA-III | Carbonate dehydratase III | Carbonic anhydrase 3 | Carbonic anhydrase III | CAH3_BOVIN | CA3 | Carbonic anhydrase 3 (CA III)
Type:
Enzyme
Mol. Mass.:
29376.92
Organism:
Bovine
Description:
Q3SZX4
Residue:
260
Sequence:
MAKEWGYADHNGPDHWHELFPNAKGENQSPIELNTKEISHDPSLKPWTASYDPGSAKTILNNGKTCRVVFDDTYDRSMLRGGPLAAPYRLRQFHLHWGSSDDHGSEHSVDGVKYAAELHLVHWNSKYNSYATALKHADGIAVVGVFLKIGREKGEFQLLLDALDKIKTKGKEAPFNNFNPSCLFPACRDYWTYHGSFTTPPCEECIVWLLLKEPITVSSDQIAKLRTLYSSAENEPPVPLVRNWRPPQPIKGRIVKASFK
  
Inhibitor
Name:
BDBM23416
Synonyms:
(+)-Catechin | CHEMBL311498 | (2R,3S)-2-(3,4-dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3,5,7-triol | D-Catechin | Catechin | α-CA inhibitor, 3
Type:
Flavonol
Emp. Form.:
C15H14O6
Mol. Mass.:
290.08
SMILES:
O[C@H]1Cc2c(O)cc(O)cc2O[C@@H]1c1ccc(O)c(O)c1 |r|
Structure:
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