Reaction Details Report a problem with these data
Target
Translocator protein
Ligand
BDBM50363527
Substrate
n/a
Meas. Tech.
In Vitro Potency Assay
pH
7.4±n/a
Ki
0.68±n/a nM
Comments
extracted
Citation
Wadsworth, HJ; Shan, B; O'Shea, D; Passmore, JM; Trigg, WJ Imaging neuroinflammation US Patent US9481685 Publication Date 11/1/2016
More Info.:
Target
Name:
Translocator protein
Synonyms:
Benzodiazepine receptors; peripheral & central | Bzrp | Mbr | Mitochondrial benzodiazepine receptor | PBR | PKBS | Peripheral benzodiazepine receptor (PBR) | Peripheral-Type Benzodiazepine Receptor | TSPO_RAT | Tspo
Type:
Mitochondrion membrane protein
Mol. Mass.:
18945.84
Organism:
Rattus norvegicus (rat)
Description:
Competitive binding experiments were performed on rat kidney mitochondrial membranes.
Residue:
169
Sequence:
MSQSWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAMGYGSYIIWKELGGFTEEAMVPLGLYTGQLALNWAWPPIFFGARQMGWALVDLMLVSGVATATTLAWHRVSPPAARLLYPYLAWLAFATMLNYYVWRDNSGRRGGSRLTE