Reaction Details Report a problem with these data
Target
HIV-1 protease
Ligand
BDBM468570
Substrate
n/a
Meas. Tech.
Enzyme Inhibition of Purified HIV-1 Protease
IC50
0.462±n/a nM
Citation
 Jude-Fishburn, CS; VanderVeen, LA; Riley, TA Protease inhibitors having enhanced features US Patent  US10806794 Publication Date 10/20/2020 
Target
Name:
HIV-1 protease
Synonyms:
HIV-1 protease wild type
Type:
Protein
Mol. Mass.:
10757.68
Organism:
Human immunodeficiency virus
Description:
O90785
Residue:
99
Sequence:
PQITLWQRPLVTVKIGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYEQVLIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF
  
Inhibitor
Name:
BDBM468570
Synonyms:
US10806794, Compound mPEG5-OCONH-Tipranavir
Type:
Small organic molecule
Emp. Form.:
C43H56F3N3O12S
Mol. Mass.:
895.978
SMILES:
CC[C@@H](C1=C(O)C[C@@](CCCNC(=O)OCCOCCOCCOCCOCCOC)(CCc2ccccc2)OC1=O)c1cccc(NS(=O)(=O)c2ccc(cn2)C(F)(F)F)c1 |r,c:3|
Structure:
Search PDB for entries with ligand similarity: