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Target
Indoleamine 2,3-dioxygenase 1
Ligand
BDBM168434
Substrate
n/a
Meas. Tech.
IDO Kynurenine Assay
Temperature
298.1500±n/a K
EC50
126±n/a nM
Comments
extracted
Citation
 PubChem, PC; Balog, JA; Huang, A; Chen, B; Chen, L; Seitz, SP; Hart, AC; Markwalder, JA Inhibitors of indoleamine 2,3-dioxygenase (IDO) US Patent  US9675571 Publication Date 6/13/2017 
Target
Name:
Indoleamine 2,3-dioxygenase 1
Synonyms:
IDO-1 | Indoleamine 2,3-Dioxygenasae (IDO) | Indoleamine-pyrrole 2,3-dioxygenase | I23O1_HUMAN | IDO1 | IDO | INDO | Indoleamine 2,3-dioxygenase
Type:
Enzyme
Mol. Mass.:
45330.80
Organism:
Human
Description:
P14902
Residue:
403
Sequence:
MAHAMENSWTISKEYHIDEEVGFALPNPQENLPDFYNDWMFIAKHLPDLIESGQLRERVEKLNMLSIDHLTDHKSQRLARLVLGCITMAYVWGKGHGDVRKVLPRNIAVPYCQLSKKLELPPILVYADCVLANWKKKDPNKPLTYENMDVLFSFRDGDCSKGFFLVSLLVEIAAASAIKVIPTVFKAMQMQERDTLLKALLEIASCLEKALQVFHQIHDHVNPKAFFSVLRIYLSGWKGNPQLSDGLVYEGFWEDPKEFAGGSAGQSSVFQCFDVLLGIQQTAGGGHAAQFLQDMRRYMPPAHRNFLCSLESNPSVREFVLSKGDAGLREAYDACVKALVSLRSYHLQIVTKYILIPASQQPKENKTSEDPSKLEAKGTGGTDLMNFLKTVRSTTEKSLLKEG
  
Inhibitor
Name:
BDBM168434
Synonyms:
US9675571, 118
Type:
Small organic molecule
Emp. Form.:
n/a
Mol. Mass.:
n/a
SMILES:
CC(C)CN(CC(C)C)c1ccc(cc1NC(=O)Cc1ccc(C)nc1)[C@H]1C[C@H]1C(O)=O |r|
Structure:
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