Reaction Details Report a problem with these data
Target
Amyloid-beta precursor protein [1-42]
Ligand
BDBM50492518
Substrate
n/a
Meas. Tech.
In Vitro Inhibition Assay
Ki
2.20±1 nM
Citation
 Routier, S; Suzenet, F; Chalon, S; Buron, F; Vercouillie, J; Melki, R; Boiaryna, L; Guilloteau, D; Pieri, L Compounds for using in imaging and particularly for the diagnosis of neurodegenerative diseases US Patent  US10906900 Publication Date 2/2/2021 
Target
Name:
Amyloid-beta precursor protein [1-42]
Synonyms:
A4 | A4_HUMAN | AD1 | APP | Amyloid-beta precursor protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
3256.81
Organism:
Homo sapiens (Human)
Description:
aa 1-42
Residue:
32
Sequence:
MLPGLALLLLAAWTARALEVPTDGNAGLLAEP
  
Inhibitor
Name:
BDBM50492518
Synonyms:
Florbetapir | US10906900, AV45
Type:
Small organic molecule
Emp. Form.:
C20H25FN2O3
Mol. Mass.:
360.4225
SMILES:
CNc1ccc(\C=C\c2ccc(OCCOCCOCCF)nc2)cc1
Structure:
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