Target
Amyloid-beta precursor protein [1-42]
Ligand
BDBM481149
Substrate
n/a
Meas. Tech.
In Vitro Inhibition Assay
Ki
24.5±9 nM
Citation
 Routier, SSuzenet, FChalon, SBuron, FVercouillie, JMelki, RBoiaryna, LGuilloteau, DPieri, L Compounds for using in imaging and particularly for the diagnosis of neurodegenerative diseases US Patent  US10906900 Publication Date 2/2/2021 
Target
Name:
Amyloid-beta precursor protein [1-42]
Synonyms:
A4 | A4_HUMAN | AD1 | APP | Amyloid-beta precursor protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
3256.81
Organism:
Homo sapiens (Human)
Description:
aa 1-42
Residue:
32
Sequence:
MLPGLALLLLAAWTARALEVPTDGNAGLLAEP
  
Inhibitor
Name:
BDBM481149
Synonyms:
US10906900, Reference 22a
Type:
Small organic molecule
Emp. Form.:
C17H15N3
Mol. Mass.:
261.3211
SMILES:
CN(C)c1ccc(cc1)C#Cc1cc2cccnc2[nH]1
Structure:
Search PDB for entries with ligand similarity: