Reaction Details Report a problem with these data
Target
Alpha-synuclein
Ligand
BDBM50492518
Substrate
n/a
Meas. Tech.
In Vitro Direct Determination By Fluorescence
Kd
24.3±20 nM
Citation
 Routier, S; Suzenet, F; Chalon, S; Buron, F; Vercouillie, J; Melki, R; Boiaryna, L; Guilloteau, D; Pieri, L Compounds for using in imaging and particularly for the diagnosis of neurodegenerative diseases US Patent  US10906900 Publication Date 2/2/2021 
Target
Name:
Alpha-synuclein
Synonyms:
NACP | PARK1 | SNCA | SYUA_HUMAN
Type:
Protein
Mol. Mass.:
14451.42
Organism:
Homo sapiens (Human)
Description:
P37840
Residue:
140
Sequence:
MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA
  
Inhibitor
Name:
BDBM50492518
Synonyms:
Florbetapir | US10906900, AV45
Type:
Small organic molecule
Emp. Form.:
C20H25FN2O3
Mol. Mass.:
360.4225
SMILES:
CNc1ccc(\C=C\c2ccc(OCCOCCOCCF)nc2)cc1
Structure:
Search PDB for entries with ligand similarity: