Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM301741
Substrate
n/a
Meas. Tech.
Pharmacological Assay
EC50
58.0±n/a nM
Citation
 Eckhardt, M; Frattini, S; Langkopf, E; Wagner, H Indanyloxydihydrobenzofuranylacetic acids US Patent  US9597310 Publication Date 3/21/2017 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM301741
Synonyms:
2-(3,5-Difluoro-4-(3-(methylsulfonyl)propoxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane | US9597310, 31
Type:
Small organic molecule
Emp. Form.:
C32H29F3N2O6
Mol. Mass.:
594.5777
SMILES:
CC(C)(O)Cn1cc(cn1)-c1cc(F)c(Oc2ccc(F)c3[C@@H](CCc23)Oc2ccc3[C@H](CC(O)=O)COc3c2)c(F)c1 |r|
Structure:
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