Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM301759
Substrate
n/a
Meas. Tech.
Pharmacological Assay
EC50
17.0±n/a nM
Citation
 Eckhardt, M; Frattini, S; Langkopf, E; Wagner, H Indanyloxydihydrobenzofuranylacetic acids US Patent  US9597310 Publication Date 3/21/2017 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM301759
Synonyms:
((S)-6-{(R)-4-[4-(3,6-Dihydro-2H-pyran-4-yl)-phenoxy]-7-fluoro-indan-1-yloxy}-2,3-dihydro-benzofuran-3-yl)-acetic acid methyl ester | US9597310, 49
Type:
Small organic molecule
Emp. Form.:
C31H31FO6
Mol. Mass.:
518.5726
SMILES:
COC(=O)C[C@@H]1COc2cc(O[C@@H]3CCc4c3c(F)ccc4Oc3ccc(cc3)C3CCOCC3)ccc12 |r|
Structure:
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