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Found 9 of affinity data for UniProtKB/TrEMBL: O60656
TargetUDP-glucuronosyltransferase 1A9(Homo sapiens (Human))
The University Of British Columbia

Curated by ChEMBL
LigandPNGBDBM13066(2-{2-[(2,6-dichlorophenyl)amino]phenyl}acetic acid...)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition of 4-methylumbelliferone glucuronidation by human recombinant UGT1A9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A9(Homo sapiens (Human))
The University Of British Columbia

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  3.44E+5nMAssay Description:Drug metabolism assessed as recombinant human UGT1A9 assessed as O-glucuronidation measured as inhibition constant at 10 to 400 uM incubated for 60 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetUDP-glucuronosyltransferase 1A9(Homo sapiens (Human))
The University Of British Columbia

Curated by ChEMBL
LigandPNGBDBM50088502(CHEBI:5970 | CHEMBL3527329)
Affinity DataKi:  5.34E+5nMAssay Description:Substrate inhibition of human recombinant UGT1A9 assessed as IRI-O-5-monoglucuronide formation incubated for 5 mins prior to UDPGA addition measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A9(Homo sapiens (Human))
The University Of British Columbia

Curated by ChEMBL
LigandPNGBDBM50008347(5-(2-(diethylamino)ethylamino)-8-hydroxy-6H-imidaz...)
Affinity DataKi:  9.58E+5nMAssay Description:Inhibition of human recombinant UGT1A9 activity expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A9(Homo sapiens (Human))
The University Of British Columbia

Curated by ChEMBL
LigandPNGBDBM50088499(CHEMBL329092)
Affinity DataKi:  1.65E+6nMAssay Description:Inhibition of human recombinant UGT1A9 activity expressed in baculovirus-infected Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A9(Homo sapiens (Human))
The University Of British Columbia

Curated by ChEMBL
LigandPNGBDBM50206509(4-Dipropylsulfamoyl-benzoic acid | 4-Dipropylsulfa...)
Affinity DataKi:  2.45E+6nMAssay Description:Inhibition of 4-methylumbelliferone glucuronidation by human recombinant UGT1A9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A9(Homo sapiens (Human))
The University Of British Columbia

Curated by ChEMBL
LigandPNGBDBM50511112(CHEMBL4567446)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of UGT1A9 in human liver microsomes incubated for 30 mins in presence of UDPGA by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetUDP-glucuronosyltransferase 1A9(Homo sapiens (Human))
The University Of British Columbia

Curated by ChEMBL
LigandPNGBDBM50508419(CHEMBL4471264)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of UGT1A9 in human liver microsomes assessed as reduction in mycophenolic acid glucuronidation by tandem mass spectrometry analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-glucuronosyltransferase 1A9(Homo sapiens (Human))
The University Of British Columbia

Curated by ChEMBL
LigandPNGBDBM50103451(CHEMBL3398252)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of of UGT1A9 in pooled mixed-gender human liver microsomes using 4-methylumbelliferone substrate by HPLC methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed