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Found 85 of affinity data for UniProtKB/TrEMBL: O88693
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50602025(CHEMBL5181454)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of mouse GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50602022(CHEMBL5197585)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of mouse GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50602024(CHEMBL5178033)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of mouse GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hrs by Rapidfire mass spectrometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50335382(CHEMBL1651638 | N-Octoxypentyl-L-ido-1-deoxynojiri...)
Affinity DataIC50:  50nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50335383(CHEMBL1651637 | N-Heptoxypentyl-L-ido-1-deoxynojir...)
Affinity DataIC50:  50nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50585893(CHEMBL5078078)
Affinity DataIC50:  51nMAssay Description:Inhibition of mouse GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hr by RapidFire mass spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50335384(CHEMBL1651636 | N-Hexoxypentyl-L-ido-1-deoxynojiri...)
Affinity DataIC50:  100nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50312527(CHEMBL1086996 | N-[5-(Adamantan-1-yl-methoxy)-pent...)
Affinity DataIC50:  100nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50312527(CHEMBL1086996 | N-[5-(Adamantan-1-yl-methoxy)-pent...)
Affinity DataIC50:  100nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50335387(CHEMBL1651633 | N-Nonoxypentyl-1-deoxynojirimycin)
Affinity DataIC50:  100nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50335385(CHEMBL1651635 | N-Pentoxypentyl-L-ido-1-deoxynojir...)
Affinity DataIC50:  150nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50585896(CHEMBL5085509)
Affinity DataIC50:  190nMAssay Description:Inhibition of mouse GCS using C8-ceramide and UDP-glucose as substrate incubated for 1 hr by RapidFire mass spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50335388(CHEMBL1651632 | N-Octoxypentyl-1-deoxynojirimycin)
Affinity DataIC50:  200nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299749((2R,3R,4R,5S)-1-[5-(Adamantan-1-ylmethoxy)-pentyl]...)
Affinity DataIC50:  200nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50299749((2R,3R,4R,5S)-1-[5-(Adamantan-1-ylmethoxy)-pentyl]...)
Affinity DataIC50:  200nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50335389(CHEMBL1651631 | N-Heptoxypentyl-1-deoxynojirimycin)
Affinity DataIC50:  300nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50379037(CHEMBL2011641)
Affinity DataIC50:  800nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50335390(CHEMBL1651630 | N-Hexoxypentyl-1-deoxynojirimycin)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50335393(CHEMBL1651627 | N-Nonyl-L-ido-1-deoxynojirimycin)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50335386(CHEMBL1651634 | N-Butoxypentyl-L-ido-1-deoxynojiri...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50335391(CHEMBL1651629 | N-Pentoxypentyl-1-deoxynojirimycin)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50335394(CHEMBL1651626 | N-Octyl-L-ido-1-deoxynojirimycin)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM18358((2R,3R,4R,5S)-2-(hydroxymethyl)-1-nonylpiperidine-...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50335392(CHEMBL1651628 | N-Butoxypentyl-1-deoxynojirimycin)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50335395(CHEMBL1651555 | N-Heptyl-L-ido-1-deoxynojirimycin)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM18357((2R,3R,4R,5S)-2-(hydroxymethyl)-1-octylpiperidine-...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated with compound for 15 mins by in-situ enzyme inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50242629(CHEMBL485842 | N-butylgalactonojirimycin)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition mouse glucosylceramide synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50379024(CHEMBL1818437)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50379025(CHEMBL2011631)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50379026(CHEMBL2011632)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50292389(3-epi-fagomine | 3-epifagomine | CHEMBL456583)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50379027(CHEMBL2011633)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50379028(CHEMBL2011634)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50379029(CHEMBL2011635)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50379030(CHEMBL2011636)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50379031(CHEMBL1818435)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50379032(CHEMBL2011637)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50379033(CHEMBL2011638)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50379034(CHEMBL1818439)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50379035(CHEMBL2011639)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50379036(CHEMBL2011640)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50379038(CHEMBL2011642)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50379039(CHEMBL2011627)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50379040(CHEMBL2011611)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50379041(CHEMBL2011612)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50379042(CHEMBL2011613)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50379043(CHEMBL2011614)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50379044(CHEMBL2011615)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50379045(CHEMBL2011616)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCeramide glucosyltransferase(Mus musculus)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50379046(CHEMBL2011617)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of glucosylceramide synthase in mouse RAW cells preincubated for 15 mins followed by substrate addition and measured after 1 hr by fluores...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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