Compile Data Set for Download or QSAR
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Found 186 of affinity data for UniProtKB/TrEMBL: P14137
LigandPNGBDBM83720(6-(2-naphthalenylsulfonyl)quinazoline-2,4-diamine ...)
Affinity DataIC50:  0.0200nMAssay Description:Antibacterial activity against Streptococcus faecalis assessed as growth inhibitionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50350465(AMPICILLIN | AY-6108 | Amcill | Aminobenzylpenicil...)
Affinity DataIC50:  28.6nMAssay Description:Antibacterial activity against Streptococcus faecalis by broth microdilution techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM21690(1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,...)
Affinity DataIC50:  36.2nMAssay Description:Antibacterial activity against Enterococcus faecalis MTCC 439 incubated overnight by broth dilution techniqueMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50335519((S)-3,6-Diamino-hexanoic acid {(3S,9S,12S,15S)-3-(...)
Affinity DataIC50:  41.4nMAssay Description:Antibacterial activity against gram positive bacteria Enterococcus faecalis was determined by twofold Micro-broth dilution assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50498223(CHEMBL3577359)
Affinity DataIC50:  167nMAssay Description:Antibacterial activity against Enterococcus faecalis ATCC 51299 assessed as growth inhibition using fresh sample in DMSO by CLSI methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50225960(CHEMBL310176)
Affinity DataIC50:  219nMAssay Description:Concentration (IC50) to inhibit the growth of Streptococcus faecalis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50225959(CHEMBL307316)
Affinity DataIC50:  401nMAssay Description:Concentration (IC50) to inhibit the growth of Streptococcus faecalis.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50476074(Gentamicin | SCH-9724 | Uromycine)
Affinity DataIC50:  445nMAssay Description:Antibacterial activity against Streptococcus faecalis by broth microdilution techniqueMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50600678(CHEMBL5176174)
Affinity DataIC50:  500nMAssay Description:Antibacterial activity against Enterococcus faecalis incubated for 16 to 24 hrs by broth microdilution based spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM21690(1-cyclopropyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,...)
Affinity DataIC50:  603nMAssay Description:Antibacterial activity against Enterococcus faecalis ATCC 51299 assessed as growth inhibition using fresh sample in DMSO by CLSI methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50366826(DR-3355 | Floxacin | Iquix | LEVOFLOXACIN | Levaqu...)
Affinity DataIC50:  1.00E+3nMAssay Description:Antibacterial activity against vancomycin-resistant Enterococcus faecalis ATCC 51299 after 18 hrs by broth microdilution methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50366826(DR-3355 | Floxacin | Iquix | LEVOFLOXACIN | Levaqu...)
Affinity DataIC50:  1.00E+3nMAssay Description:Antibacterial activity against vancomycin-sensitive Enterococcus faecalis 12-5 after 18 hrs by broth microdilution methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50509323(CHEMBL4436622)
Affinity DataIC50:  1.00E+3nMAssay Description:Antibacterial activity against vancomycin-resistant Enterococcus faecalis AUS-RBWH-VRE-01 assessed as reduction in fungal growth incubated for 24 hrs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50366826(DR-3355 | Floxacin | Iquix | LEVOFLOXACIN | Levaqu...)
Affinity DataIC50:  1.00E+3nMAssay Description:Antibacterial activity against vancomycin-sensitive Enterococcus faecalis ATCC 29212 after 18 hrs by broth microdilution methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  1.24E+3nMAssay Description:Inhibition of cholesterol side chain cleavage cytochrome P450More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50497194(CHEMBL3116168)
Affinity DataIC50:  1.44E+3nMAssay Description:Antimicrobial activity against Enterococcus faecalis assessed as inhibition of biofilm formation after 20 hrs by crystal violet staining analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50237605(Achromycin | Achromycin V | CHEBI:27902 | Cyclopar...)
Affinity DataIC50:  1.57E+3nMAssay Description:Antibacterial activity against vancomycin-resistant Enterococcus faecalis ATCC 51299 after 18 hrs by broth dilution assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50509324(CHEMBL4463460)
Affinity DataIC50:  1.60E+3nMAssay Description:Antibacterial activity against vancomycin-resistant Enterococcus faecalis AUS-RBWH-VRE-01 assessed as reduction in fungal growth incubated for 24 hrs...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50478886(CHEMBL501116)
Affinity DataIC50:  2.00E+3nMAssay Description:Antibacterial activity against vancomycin-resistant Enterococcus faecalis ATCC 51299 after 18 hrs by broth dilution assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50497201(CHEMBL3116167)
Affinity DataIC50:  2.17E+3nMAssay Description:Antimicrobial activity against Enterococcus faecalis assessed as inhibition of biofilm formation after 20 hrs by crystal violet staining analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50103513(CHEBI:17076 | Chemform | Gerox | NSC-14083 | Strep...)
Affinity DataIC50:  2.23E+3nMAssay Description:Antibacterial activity against gram positive bacteria Enterococcus faecalis was determined by twofold Micro-broth dilution assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50499513(CHEMBL4299436)
Affinity DataIC50:  2.27E+3nMAssay Description:Antibacterial activity against low level vancomycin-resistant Enterococcus faecalis ATCC 51299 by plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50497203(CHEMBL3115985)
Affinity DataIC50:  2.29E+3nMAssay Description:Antimicrobial activity against Enterococcus faecalis assessed as inhibition of biofilm formation after 20 hrs by crystal violet staining analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50335519((S)-3,6-Diamino-hexanoic acid {(3S,9S,12S,15S)-3-(...)
Affinity DataIC50:  2.34E+3nMAssay Description:Antibacterial activity against Enterococcus faecalis ATCC 51299 assessed as growth inhibition using fresh sample in DMSO by CLSI methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50497199(CHEMBL3115992)
Affinity DataIC50:  2.38E+3nMAssay Description:Antimicrobial activity against Enterococcus faecalis assessed as inhibition of biofilm formation after 20 hrs by crystal violet staining analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50497204(CHEMBL3115986)
Affinity DataIC50:  2.39E+3nMAssay Description:Antimicrobial activity against Enterococcus faecalis assessed as inhibition of biofilm formation after 20 hrs by crystal violet staining analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50218278(CHEMBL279571)
Affinity DataIC50:  2.50E+3nMAssay Description:Compound was evaluated for inhibition of peptidoglycan synthesis in Enterococcus faecalis using [14C]lysine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50335519((S)-3,6-Diamino-hexanoic acid {(3S,9S,12S,15S)-3-(...)
Affinity DataIC50:  2.60E+3nMAssay Description:Compound was evaluated for inhibition of peptidoglycan synthesis in Enterococcus faecalis using [14C]lysine radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50600667(CHEMBL5180164)
Affinity DataIC50:  2.70E+3nMAssay Description:Antibacterial activity against Enterococcus faecalis incubated for 16 to 24 hrs by broth microdilution based spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50498339(CHEMBL3585711)
Affinity DataIC50:  2.72E+3nMAssay Description:Antibacterial activity against Enterococcus faecalis CECT 481 assessed as inhibition of microbial growth incubated for 18 hrs by 2-fold microtiter br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50497190(CHEMBL3115993)
Affinity DataIC50:  2.85E+3nMAssay Description:Antimicrobial activity against Enterococcus faecalis assessed as inhibition of biofilm formation after 20 hrs by crystal violet staining analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50004442((2S,4S)-ketoconazole | 1-acetyl-4-(4-{[(2S,4S)-2-(...)
Affinity DataIC50:  2.95E+3nMAssay Description:Inhibition of cholesterol side chain cleavage cytochrome P450More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50600670(CHEMBL5204687)
Affinity DataIC50:  3.00E+3nMAssay Description:Antibacterial activity against Enterococcus faecalis incubated for 16 to 24 hrs by broth microdilution based spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50498341(CHEMBL3585709)
Affinity DataIC50:  3.06E+3nMAssay Description:Antibacterial activity against Enterococcus faecalis CECT 481 assessed as inhibition of microbial growth incubated for 18 hrs by 2-fold microtiter br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50600662(CHEMBL5193721)
Affinity DataIC50:  3.10E+3nMAssay Description:Antibacterial activity against Enterococcus faecalis incubated for 16 to 24 hrs by broth microdilution based spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50497191(CHEMBL3116162)
Affinity DataIC50:  3.14E+3nMAssay Description:Antimicrobial activity against Enterococcus faecalis assessed as inhibition of biofilm formation after 20 hrs by crystal violet staining analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50498340(CHEMBL3585717)
Affinity DataIC50:  3.19E+3nMAssay Description:Antibacterial activity against Enterococcus faecalis CECT 481 assessed as inhibition of microbial growth incubated for 18 hrs by 2-fold microtiter br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50498338(CHEMBL3585716)
Affinity DataIC50:  3.66E+3nMAssay Description:Antibacterial activity against Enterococcus faecalis CECT 481 assessed as inhibition of microbial growth incubated for 18 hrs by 2-fold microtiter br...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50497202(CHEMBL3115977)
Affinity DataIC50:  3.69E+3nMAssay Description:Antimicrobial activity against Enterococcus faecalis assessed as inhibition of biofilm formation after 20 hrs by crystal violet staining analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50600671(CHEMBL5175684)
Affinity DataIC50:  3.70E+3nMAssay Description:Antibacterial activity against Enterococcus faecalis incubated for 16 to 24 hrs by broth microdilution based spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50004441((2R,4R)-ketoconazole | 1-acetyl-4-(4-{[(2R,4R)-2-(...)
Affinity DataIC50:  3.92E+3nMAssay Description:Inhibition of cholesterol side chain cleavage cytochrome P450More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50497011(CHEMBL3234400)
Affinity DataIC50:  4.00E+3nMAssay Description:Antibacterial activity against vancomycin-sensitive Enterococcus faecalis 12-5 after 18 hrs by broth microdilution methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50600666(CHEMBL5178722)
Affinity DataIC50:  4.00E+3nMAssay Description:Antibacterial activity against Enterococcus faecalis incubated for 16 to 24 hrs by broth microdilution based spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50497011(CHEMBL3234400)
Affinity DataIC50:  4.00E+3nMAssay Description:Antibacterial activity against vancomycin-sensitive Enterococcus faecalis ATCC 29212 after 18 hrs by broth microdilution methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50497011(CHEMBL3234400)
Affinity DataIC50:  4.00E+3nMAssay Description:Antibacterial activity against vancomycin-resistant Enterococcus faecalis 09-9 after 18 hrs by broth microdilution methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50497011(CHEMBL3234400)
Affinity DataIC50:  4.00E+3nMAssay Description:Antibacterial activity against vancomycin-resistant Enterococcus faecalis ATCC 51299 after 18 hrs by broth microdilution methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM31768(CHEMBL295698 | Ketoconazole | Nizoral | Panfungol)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of cytochrome P450 19A1 involved in steroid biosynthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50222406(CHEMBL430074)
Affinity DataIC50:  5.65E+3nMAssay Description:Inhibitory activity of compound against VanA Enterococcus faecalis MGH-01More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50600660(CHEMBL5187573)
Affinity DataIC50:  5.70E+3nMAssay Description:Antibacterial activity against Enterococcus faecalis incubated for 16 to 24 hrs by broth microdilution based spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
LigandPNGBDBM50497193(CHEMBL3116165)
Affinity DataIC50:  5.96E+3nMAssay Description:Antimicrobial activity against Enterococcus faecalis assessed as inhibition of biofilm formation after 20 hrs by crystal violet staining analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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