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Found 1059 for UniProtKB: P26684
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50000558(CHEMBL437472 | ET-1 | Endothelin -1 | Endothelin 1...)
Affinity DataKi:  0.0340nMAssay Description:Compound was evaluated for the binding affinity to Endothelin A receptor in the rat atriumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50143784((5S,6R,7R)-5-Benzo[1,3]dioxol-5-yl-2-butyl-7-[2-((...)
Affinity DataKi:  0.0340nMAssay Description:Binding affinity towards Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051007((2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbam...)
Affinity DataKi:  0.0340nMAssay Description:Binding affinity towards Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50051007((2R,3R,4S)-4-Benzo[1,3]dioxol-5-yl-1-dibutylcarbam...)
Affinity DataKi:  0.0470nMAssay Description:binding affinity against human Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368606(Sarafotoxin S6B)
Affinity DataKi:  0.0870nMAssay Description:Compound was evaluated for the binding affinity to Endothelin A receptor in the rat atriumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50000558(CHEMBL437472 | ET-1 | Endothelin -1 | Endothelin 1...)
Affinity DataKi:  0.110nMAssay Description:Compound was evaluated for the binding affinity to Endothelin A receptor in the rat aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368606(Sarafotoxin S6B)
Affinity DataKi:  0.240nMAssay Description:Compound was evaluated for the binding affinity to Endothelin A receptor in the rat atriumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50058126(2-[2-(6-Methyl-benzo[1,3]dioxol-5-yl)-acetyl]-thio...)
Affinity DataKi:  0.430nMAssay Description:Binding affinity towards Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50091105(4''-Oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dime...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [125I]-ET1 from ETA receptor in A10 rat thoracic aorta smooth muscle after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50091105(4''-Oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dime...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [125I]-ET1 from ETA receptor in A10 rat thoracic aorta smooth muscle after 3 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50091105(4''-Oxazol-2-yl-biphenyl-2-sulfonic acid (3,4-dime...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity towards Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068673(2'-Formylaminomethyl-4'-isobutyl-biphenyl-2-sulfon...)
Affinity DataKi:  2nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368607(CHEMBL1790180)
Affinity DataKi:  2.5nMAssay Description:Compound was evaluated for the binding affinity to Endothelin A receptor in the rat aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50368607(CHEMBL1790180)
Affinity DataKi:  2.5nMAssay Description:Compound was evaluated for the binding affinity to Endothelin A receptor in the rat aortaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068706(6-(2-Hydroxy-ethoxy)-4'-isobutyl-biphenyl-2-sulfon...)
Affinity DataKi:  2.70nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068674(2'-Amino-4'-isobutyl-biphenyl-2-sulfonic acid (3,4...)
Affinity DataKi:  4.70nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068713(4'-Isobutyl-2'-methyl-biphenyl-2-sulfonic acid (3,...)
Affinity DataKi:  5nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068720(6-Hydroxy-4'-isobutyl-biphenyl-2-sulfonic acid (3,...)
Affinity DataKi:  5nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50108202((S)-2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-methoxy-...)
Affinity DataKi:  6nMAssay Description:Binding affinity towards Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068740(2'-Ethylamino-4'-isobutyl-biphenyl-2-sulfonic acid...)
Affinity DataKi:  6.30nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068697(2'-(2-Hydroxy-ethylamino)-4'-isobutyl-biphenyl-2-s...)
Affinity DataKi:  6.40nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50061101(4-(1,1-Dimethylethyl)-N-(6-(2-hydroxyethoxy)-5-(2-...)
Affinity DataKi:  6.5nMAssay Description:Binding affinity towards Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068736(2'-Hydroxy-4'-isobutyl-biphenyl-2-sulfonic acid (3...)
Affinity DataKi:  8nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068685(4'-Isobutyl-biphenyl-2-sulfonic acid (4,5-dimethyl...)
Affinity DataKi:  13nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068704(4'-Isobutyl-2'-methylamino-biphenyl-2-sulfonic aci...)
Affinity DataKi:  14nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068722(5-Amino-4'-isobutyl-biphenyl-2-sulfonic acid (3,4-...)
Affinity DataKi:  14nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068719(4'-Isobutyl-6-methoxy-biphenyl-2-sulfonic acid (3,...)
Affinity DataKi:  16nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068716(2'-Amino-biphenyl-2-sulfonic acid (3,4-dimethyl-is...)
Affinity DataKi:  16nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068676(4'-Isopropoxy-biphenyl-2-sulfonic acid (3,4-dimeth...)
Affinity DataKi:  17nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068717(2'-Formylamino-4'-isobutyl-biphenyl-2-sulfonic aci...)
Affinity DataKi:  17nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068742(4'-Isobutyl-biphenyl-2-sulfonic acid (3,4-dimethyl...)
Affinity DataKi:  18nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068729(2'-Fluoro-4'-isobutyl-biphenyl-2-sulfonic acid (3,...)
Affinity DataKi:  20nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068698(2'-Hydroxymethyl-4'-isobutyl-biphenyl-2-sulfonic a...)
Affinity DataKi:  20nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068694(4'-Propyl-biphenyl-2-sulfonic acid (3,4-dimethyl-i...)
Affinity DataKi:  28nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068677(4'-Isobutyl-2'-propylamino-biphenyl-2-sulfonic aci...)
Affinity DataKi:  29nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068686(4'-Isobutoxy-biphenyl-2-sulfonic acid (3,4-dimethy...)
Affinity DataKi:  32nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068746(4'-Methoxy-biphenyl-2-sulfonic acid (3,4-dimethyl-...)
Affinity DataKi:  33nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068738(4'-Isobutyl-2'-isopropylamino-biphenyl-2-sulfonic ...)
Affinity DataKi:  34nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068735(4'-Butyl-biphenyl-2-sulfonic acid (3,4-dimethyl-is...)
Affinity DataKi:  37nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068731(4'-Isopropylsulfanyl-biphenyl-2-sulfonic acid (3,4...)
Affinity DataKi:  39nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50329850((R)-3-Amino-4-[(S)-2-((R)-1-{(S)-1-[(R)-1-(1H-indo...)
Affinity DataKi:  40nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068703(2'-Hydroxymethyl-biphenyl-2-sulfonic acid (3,4-dim...)
Affinity DataKi:  40nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068691(CHEMBL149152 | Lithium; [6-(3,4-dimethyl-isoxazol-...)
Affinity DataKi:  42nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068710(4'-Isobutyl-2'-(3-methyl-ureido)-biphenyl-2-sulfon...)
Affinity DataKi:  43nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068705(4'-Isopropyl-biphenyl-2-sulfonic acid (3,4-dimethy...)
Affinity DataKi:  50nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068727(4'-Isopropylamino-biphenyl-2-sulfonic acid (3,4-di...)
Affinity DataKi:  50nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068682(4'-Dimethylamino-biphenyl-2-sulfonic acid (3,4-dim...)
Affinity DataKi:  54nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50034435(5-Dimethylamino-naphthalene-1-sulfonic acid (3,4-d...)
Affinity DataKi:  55nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068701(4'-Methyl-biphenyl-2-sulfonic acid (3,4-dimethyl-i...)
Affinity DataKi:  55nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEndothelin-1 receptor(RAT)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50068683(4'-(Isopropyl-methyl-amino)-biphenyl-2-sulfonic ac...)
Affinity DataKi:  60nMAssay Description:Ability to inhibit binding of [125I]ET1 to membranes prepared from A10 rat thoracic aorta smooth muscle Endothelin A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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