Affinity DataKi: 0.772nMAssay Description:Displacement of [33P]-S1P from human S1P2 receptor expressed in CHO-K1 cells after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataEC50: 0.310nMAssay Description:Agonist activity at rat S1P1 expressed in CHO cell membranes assessed as stimulation of [35S]-GTPgamma-S binding measured after 45 mins by liquid sci...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0500nMAssay Description:Agonist activity at rat S1P1 receptor assessed as cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0400nMAssay Description:Agonist activity at rat S1P1 receptor assessed as change in cAMP level by homogeneous time resolved fluorescence cyclase assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist activity at rat S1P1 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production after 1 hr by HTRF ass...More data for this Ligand-Target Pair
Affinity DataEC50: 1.30nMAssay Description:Agonist activity at rat S1P1 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP production after 1 hr by HTRF ass...More data for this Ligand-Target Pair
Affinity DataEC50: 0.290nMAssay Description:Agonist activity at rat S1P1 receptor expressed in CHO-K1 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataEC50: 1.80nMAssay Description:Agonist activity at rat S1P1 receptor expressed in CHO-K1 cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.290nMAssay Description:Agonist activity at rat S1P1 receptor expressed in CHO-K1 cells assessed as induction of GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 1.80nMAssay Description:Agonist activity at rat S1P1 receptor expressed in CHO-K1 cells assessed as induction of GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 1.5nMAssay Description:Agonist activity at rat S1P1 receptor expressed in CHO-K1 cells assessed as induction of GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 4.40nMAssay Description:Agonist activity at rat S1P1 receptor expressed in CHO cells assessed as stimulation of [35S]GTPgammaS binding preincubated for 30 mins followed by [...More data for this Ligand-Target Pair
Affinity DataEC50: 1.40nMAssay Description:Agonist activity against rat S1P1 assessed as accumulation of cAMP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.40nMAssay Description:Agonist activity against rat S1P1 assessed as accumulation of cAMP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.40nMAssay Description:Agonist activity against rat S1P1 assessed as accumulation of cAMP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.40nMAssay Description:Agonist activity against rat S1P1 assessed as accumulation of cAMP by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0286nMAssay Description:Agonist activity at rat S1P1 receptor assessed as inhibition of forskolin-stimulated cAMP accumulation after 30 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataEC50: 0.320nMAssay Description:Agonist activity at rat S1P1 receptor assessed as cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 0.0720nMAssay Description:Agonist activity at rat S1P1 receptor assessed as cAMP accumulation by HTRF assayMore data for this Ligand-Target Pair
