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Found 1199 for UniProtKB: P79208
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataKi:  490nMAssay Description:The enzyme kinetics were determined, wherein the arachidonic acid substrate either in the absence or presence of selected derivatives were evaluated ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM198173(2-((5-(4-Nitrophenylamino)-1,3,4-oxadiazol-2-yl)me...)
Affinity DataKi:  500nMAssay Description:The enzyme kinetics were determined, wherein the arachidonic acid substrate either in the absence or presence of selected derivatives were evaluated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM198172(2-((5-(4-Chlorophenylamino)-1,3,4-oxadiazol-2-yl)m...)
Affinity DataKi:  630nMAssay Description:The enzyme kinetics were determined, wherein the arachidonic acid substrate either in the absence or presence of selected derivatives were evaluated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM198171(2-((5-(4-Methoxyphenylamino)-1,3,4-oxadiazol-2-yl)...)
Affinity DataKi:  650nMAssay Description:The enzyme kinetics were determined, wherein the arachidonic acid substrate either in the absence or presence of selected derivatives were evaluated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM198174(2-((5-(4-Methoxyphenylamino)-1,3,4-thiadiazol-2-yl...)
Affinity DataKi:  770nMAssay Description:The enzyme kinetics were determined, wherein the arachidonic acid substrate either in the absence or presence of selected derivatives were evaluated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM198176(2-((5-(4-Nitrophenylamino)-1,3,4-thiadiazol-2-yl)m...)
Affinity DataKi:  880nMAssay Description:The enzyme kinetics were determined, wherein the arachidonic acid substrate either in the absence or presence of selected derivatives were evaluated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM198175(2-((5-(4-Chlorophenylamino)-1,3,4-thiadiazol-2-yl)...)
Affinity DataKi:  960nMAssay Description:The enzyme kinetics were determined, wherein the arachidonic acid substrate either in the absence or presence of selected derivatives were evaluated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50009859((+-)-2-(p-isobutylphenyl)propionic acid | (+-)-alp...)
Affinity DataKi:  9.00E+3nMAssay Description:Inhibition of sheep placental cotyledons COX2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataKi:  9.86E+3nMAssay Description:Competitive inhibition of ovine COX2 using arachidonic acid substrate by Ellman's spectrophotometric assay based Lineweaver-Burk double reciprocal pl...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM86694(N'-(3-Chloro-4-morpholinophenyl)-N-hydroxyform...)
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50114413(CHEMBL3608346)
Affinity DataKi:  1.45E+4nMAssay Description:Competitive inhibition of ovine COX2 using arachidonic acid substrate by Ellman's spectrophotometric assay based Lineweaver-Burk double reciprocal pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50114414(CHEMBL3608347)
Affinity DataKi:  1.46E+4nMAssay Description:Competitive inhibition of ovine COX2 using arachidonic acid substrate by Ellman's spectrophotometric assay based Lineweaver-Burk double reciprocal pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50114415(CHEMBL3608348)
Affinity DataKi:  1.47E+4nMAssay Description:Competitive inhibition of ovine COX2 using arachidonic acid substrate by Ellman's spectrophotometric assay based Lineweaver-Burk double reciprocal pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50114416(CHEMBL3608351)
Affinity DataKi:  1.48E+4nMAssay Description:Competitive inhibition of ovine COX2 using arachidonic acid substrate by Ellman's spectrophotometric assay based Lineweaver-Burk double reciprocal pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50114417(CHEMBL3608353)
Affinity DataKi:  1.48E+4nMAssay Description:Competitive inhibition of ovine COX2 using arachidonic acid substrate by Ellman's spectrophotometric assay based Lineweaver-Burk double reciprocal pl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50317931((2R*,3S*,4R*,6S*)-2-(4-Chlorophenyl)-6-((ethylthio...)
Affinity DataIC50:  0.570nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50317932((2R*,3S*,4R*,6S*)-2-(4-Chlorophenyl)tetrahydro-3,4...)
Affinity DataIC50:  0.650nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50317924((2R*,4R*,6S*)-2-(4-Chlorophenyl)tetrahydro-4-pheny...)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50088679(2-Phenyl-isoindole-1,3-dione | 2-phenyl-1H-isoindo...)
Affinity DataIC50: <1nMAssay Description:Inhibitory activity (RA2) against Prostaglandin G/H synthase 2 was calculated relative to aspirinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50219329(CHEMBL8968)
Affinity DataIC50: <1nMAssay Description:Inhibitory activity (RA2) against Prostaglandin G/H synthase 2 was calculated relative to aspirinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50066441(2-(2,6-Dimethyl-phenyl)-isoindole-1,3-dione | 2-(2...)
Affinity DataIC50: <1nMAssay Description:Inhibitory activity (RA2) against Prostaglandin G/H synthase 2 was calculated relative to aspirinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50317930((2R*,3S*,4R*,6S*)-2-(4-Fluorophenyl)tetrahydro-3,4...)
Affinity DataIC50:  1.11nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50317929((2R*,3S*,4R*,6S*)-6-((Ethylthio)methyl)-2-(4-fluor...)
Affinity DataIC50:  1.28nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50317920((2R*,4R*,6S*)-Tetrahydro-2,4-diphenyl-6-(thiocyana...)
Affinity DataIC50:  1.47nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50317928((2R*,3S*,4R*,6S*)-Tetrahydro-2,3,4-triphenyl-6-(th...)
Affinity DataIC50:  1.55nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50317927((2R*,3S*,4R*,6S*)-6-((Ethylthio)methyl)tetrahydro-...)
Affinity DataIC50:  1.72nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50317923((2R*,4R*,6S*)-2-(4-Chlorophenyl)-6-((ethylthio)met...)
Affinity DataIC50:  1.82nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50317921((2S*,4R*,6R*)-2-((Ethylthio)methyl)-6-(4-fluorophe...)
Affinity DataIC50:  2.05nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50317919((2S*,4R*,6R*)-2-((Ethylthio)methyl)tetrahydro-4,6-...)
Affinity DataIC50:  2.07nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50317933((2R*,3S*,4R*,6S*)-2-(4-Bromophenyl)-6-((ethylthio)...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50129504(6-Ethylsulfanyl-3-(4-methanesulfonyl-phenyl)-4-phe...)
Affinity DataIC50:  3.20nMAssay Description:In vitro inhibition against ovine Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50317922((2R*,4R*,6S*)-2-(4-Fluorophenyl)tetrahydro-4-pheny...)
Affinity DataIC50:  3.57nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50317926((2R*,4R*,6S*)-2-(4-Bromophenyl)tetrahydro-4-phenyl...)
Affinity DataIC50:  4.01nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50317934((2R*,3S*,4R*,6S*)-2-(4-Bromophenyl)tetrahydro-3,4-...)
Affinity DataIC50:  4.03nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50317925((2R*,4R*,6S*)-2-(4-Bromophenyl)-6-((ethylthio)meth...)
Affinity DataIC50:  5.49nMAssay Description:Inhibition of ovine COX2 assessed as inhibition of PGF2a formation after 20 mins by Ellman's methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50038399(CHEMBL3361124)
Affinity DataIC50:  9.5nMAssay Description:Inhibition of ovine COX2 using arachidonic acid substrate incubated for 5 mins by colorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50038394(CHEMBL3361119)
Affinity DataIC50: >10nMAssay Description:Inhibition of ovine COX2 using arachidonic acid substrate incubated for 5 mins by colorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50038395(CHEMBL3361120)
Affinity DataIC50: >10nMAssay Description:Inhibition of ovine COX2 using arachidonic acid substrate incubated for 5 mins by colorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50038396(CHEMBL3361121)
Affinity DataIC50: >10nMAssay Description:Inhibition of ovine COX2 using arachidonic acid substrate incubated for 5 mins by colorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50038397(CHEMBL3361122)
Affinity DataIC50: >10nMAssay Description:Inhibition of ovine COX2 using arachidonic acid substrate incubated for 5 mins by colorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50111216(5-Amino-2-((R)-3-methyl-2,6-dioxo-piperidin-3-yl)-...)
Affinity DataIC50: <10nMAssay Description:Inhibitory activity (RA2) against Prostaglandin G/H synthase 2 was calculated relative to aspirinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50038400(CHEMBL3361125)
Affinity DataIC50: >10nMAssay Description:Inhibition of ovine COX2 using arachidonic acid substrate incubated for 5 mins by colorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50038401(CHEMBL3361126)
Affinity DataIC50: >10nMAssay Description:Inhibition of ovine COX2 using arachidonic acid substrate incubated for 5 mins by colorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50038421(CHEMBL3361127)
Affinity DataIC50: >10nMAssay Description:Inhibition of ovine COX2 using arachidonic acid substrate incubated for 5 mins by colorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  10nMAssay Description:Inhibition of ovine COX2 using arachidonic acid substrate incubated for 5 mins by colorimetryMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50038398(CHEMBL3361123)
Affinity DataIC50: >10nMAssay Description:Inhibition of ovine COX2 using arachidonic acid substrate incubated for 5 mins by colorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM227578(5-(4-Methoxybenzylidene)-2-phenyl-3-(pyridin-3-yl)...)
Affinity DataIC50:  11nMpH: 8.0 T: 2°CAssay Description:Dilute 3 mL of assay buffer concentrate with 27 mL of HPLC - grade water. This final assay buffer (0.1 M Tris-HCl, pH 8) should be used for dilution ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50570875(CHEMBL4865603)
Affinity DataIC50:  11nMAssay Description:Inhibition of ovine COX-2 by colorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50325646(1-(4-Methoxyphenyl)-3-trifluoromethyl-5-(3-methyl-...)
Affinity DataIC50:  11nMAssay Description:Inhibition of sheep COX2 by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM50325644(1-(4-Chlorophenyl)-3-trifluoromethyl-5-(3-methyl-2...)
Affinity DataIC50:  11nMAssay Description:Inhibition of sheep COX2 by enzyme immunoassayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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