Compile Data Set for Download or QSAR
maximum 50k data
Found 216 of affinity data for UniProtKB/TrEMBL: Q3SYC2
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159725(US9035059, 19-4)
Affinity DataIC50:  2nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50442175(CHEMBL2441597)
Affinity DataIC50:  2nMAssay Description:Inhibition of human MGAT2 by LC/MS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50518069(CHEMBL4542050 | US11479538, Example 22)
Affinity DataIC50:  2nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM289043(US10093650, Example 20 | US10329273, Example 20 | ...)
Affinity DataIC50:  3nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50058840(CHEMBL3325734)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of human MoGAT-2 expressed in human Caco2 cells assessed as inhibition of 2-O-Hexadecylglycerol hydrolysis pretreated for 30 mins by LC-MS...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159724(US9035059, 19-3)
Affinity DataIC50:  4nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159734(US9035059, 23-1 | US9035059, 24-1/24-2)
Affinity DataIC50:  4nMT: 2°CAssay Description:An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159732(US9035059, 20-4)
Affinity DataIC50:  5nMT: 2°CAssay Description:An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM38176(US10093650, Example 2 | US10329273, Example 2 | US...)
Affinity DataIC50:  5nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM289003(US10093650, Example 14 | US10093650, Example 16 | ...)
Affinity DataIC50:  5nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM400245(US10329273, Example 16 | US11479538, Example 16)
Affinity DataIC50:  5nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM400246(US10329273, Example 17 | US11479538, Example 17)
Affinity DataIC50:  5nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159705(US9035059, 18-7)
Affinity DataIC50:  7nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50442176(CHEMBL2441598)
Affinity DataIC50:  7nMAssay Description:Inhibition of human MGAT2 by LC/MS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50442178(CHEMBL2441600 | US9187424, 124)
Affinity DataIC50:  7nMAssay Description:Inhibition of human MGAT2 by LC/MS assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50442175(CHEMBL2441597)
Affinity DataIC50:  8nMAssay Description:Inhibition of human MGAT2 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM289026(US10093650, Example 18 | US10329273, Example 18 | ...)
Affinity DataIC50:  8nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50442176(CHEMBL2441598)
Affinity DataIC50:  9nMAssay Description:Inhibition of human MGAT2 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM211296(US10093650, Example 11 | US10329273, Example 11 | ...)
Affinity DataIC50:  9nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159711(US9035059, 18-16)
Affinity DataIC50:  10nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159740(US9035059, 24-11 | US9035059, 24-5/24-6)
Affinity DataIC50:  10nMT: 2°CAssay Description:An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM289042(US10093650, Example 19 | US10329273, Example 19 | ...)
Affinity DataIC50:  10nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM289044(US10093650, Example 21 | US10329273, Example 21 | ...)
Affinity DataIC50:  10nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159734(US9035059, 23-1 | US9035059, 24-1/24-2)
Affinity DataIC50:  13nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159736(US9035059, 23-3)
Affinity DataIC50:  13nMT: 2°CAssay Description:An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159735(US9035059, 23-2)
Affinity DataIC50:  14nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159730(US9035059, 20-2)
Affinity DataIC50:  14nMT: 2°CAssay Description:An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM50442178(CHEMBL2441600 | US9187424, 124)
Affinity DataIC50:  15nMAssay Description:Inhibition of human MGAT2 by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM152809(US8993568, 5)
Affinity DataIC50:  16nMT: 2°CAssay Description:The in vitro inhibitory activity of compounds against human MOGAT-2 is evaluated in this assay. MOGAT-2 transfers an oleoyl group to monooleoyl-glyce...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159657(US9035059, 7-76)
Affinity DataIC50:  16nMT: 2°CAssay Description:An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM38181(US10093650, Example 4 | US10329273, Example 4 | US...)
Affinity DataIC50:  17nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159729(US9035059, 19-12)
Affinity DataIC50:  23nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159636(US9035059, 6-75)
Affinity DataIC50:  24nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159701(US9035059, 17-5)
Affinity DataIC50:  24nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159682(US9035059, 10-5/10-6)
Affinity DataIC50:  25nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159624(US9035059, 6-33)
Affinity DataIC50:  26nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159681(US9035059, 10-3/10-4)
Affinity DataIC50:  26nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159708(US9035059, 18-12)
Affinity DataIC50:  26nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM578481((S)-3-(5-Oxo-4,5-dihydro-1H-tetrazol-1-yl)-4-(p-to...)
Affinity DataIC50:  27nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159615(US9035059, 6-17)
Affinity DataIC50:  28nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159727(US9035059, 19-8)
Affinity DataIC50:  28nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159707(US9035059, 18-11)
Affinity DataIC50:  29nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159666(US9035059, 8-5)
Affinity DataIC50:  29nMT: 2°CAssay Description:An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159734(US9035059, 23-1 | US9035059, 24-1/24-2)
Affinity DataIC50:  29nMT: 2°CAssay Description:An MGAT2 inhibition test for test compounds was conducted in accordance with a partially modified version of the method described in John F. Lockwood...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159723(US9035059, 19-2)
Affinity DataIC50:  30nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM38204(US10093650, Example 8 | US10329273, Example 8 | US...)
Affinity DataIC50:  30nMAssay Description:The MGAT enzyme reactions were performed in Corning FALCONŽ 96-well polypropylene plates, in a total volume of 60 μL of 50 mM potassium phosphat...More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159622(US9035059, 6-31)
Affinity DataIC50:  31nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159623(US9035059, 6-32)
Affinity DataIC50:  31nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159683(US9035059, 10-7/10-8)
Affinity DataIC50:  31nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
Target2-acylglycerol O-acyltransferase 2(Homo sapiens (Human))
Taisho Pharmaceutical

US Patent
LigandPNGBDBM159718(US9035059, 18-25)
Affinity DataIC50:  33nMAssay Description:A test for MGAT2 inhibitory action of test compounds was conducted in accordance with a partially modified version of the method described in John F....More data for this Ligand-Target Pair
In DepthDetails US Patent
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