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Found 11 of affinity data for UniProtKB/TrEMBL: Q60641
TargetBile acid receptor(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM28542(WAY-362450 | XL335 | propan-2-yl 3-[(3,4-difluorop...)
Affinity DataEC50:  152nMAssay Description:Agonist activity at mouse FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306734(CHEMBL603278 | isopropyl 3-(3,4-difluorobenzoyl)-9...)
Affinity DataEC50:  112nMAssay Description:Agonist activity at mouse FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306735(1-methylethyl 8-fluoro-1,1-dimethyl-3-{[4-(3-morph...)
Affinity DataEC50:  52nMAssay Description:Agonist activity at mouse FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306744(CHEMBL601221 | Isopropyl 8-Fluoro-1,1-dimethyl-3-[...)
Affinity DataEC50:  188nMAssay Description:Agonist activity at mouse FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306714(CHEMBL601873 | Isopropyl 1,1-Dimethyl-3-[4-(3-morp...)
Affinity DataEC50:  108nMAssay Description:Agonist activity at mouse FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50600733(CHEMBL5182534)
Affinity DataEC50:  14nMAssay Description:Agonist activity at mouse LBD fused FXR in HEK293 cells incubated for 30 min by envision plate reader methodMore data for this Ligand-Target Pair
TargetBile acid receptor(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM21674((4R)-4-[(1S,2S,5R,7S,9R,10R,11S,14R,15R)-5,9-dihyd...)
Affinity DataEC50:  1.68E+4nMAssay Description:Agonist activity at mouse FXR expressed in HEK293 cells co-expressing mouse RXRalpha and ECRE-luc by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetBile acid receptor(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50359364(CHEMBL1929242)
Affinity DataEC50:  3.15E+3nMAssay Description:Agonist activity at mouse FXR expressed in HEK293 cells co-expressing mouse RXRalpha and ECRE-luc by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50359365(CHEMBL1929243)
Affinity DataEC50:  6.17E+3nMAssay Description:Agonist activity at mouse FXR expressed in HEK293 cells co-expressing mouse RXRalpha and ECRE-luc by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBile acid receptor(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50572221(CHEMBL4862974)
Affinity DataEC50:  320nMAssay Description:Agonist activity at mouse LBD fused FXR in HEK293 cells incubated for 30 min by envision plate reader methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetBile acid receptor(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50306718(CHEMBL602894 | Isopropyl 1,1-Dimethyl-3-[4-(2-morp...)
Affinity DataEC50:  190nMAssay Description:Agonist activity at mouse FXR-LBD expressed in HEL293 cells by Gal4-luciferase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed