Compile Data Set for Download or QSAR
maximum 50k data
Found 378 of affinity data for UniProtKB/TrEMBL: Q63380
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM364427(US10913711, Compound 10a | US11555013, Compound 10...)
Affinity DataKi: >0nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM364425(US10913711, Compound 10d | US11555013, Compound 10...)
Affinity DataKi: >0nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50308250((1R,5R,6R)-1-(3,4-dichlorophenyl)-6-(ethoxymethyl)...)
Affinity DataKi:  0.135nMAssay Description:Displacement of [N-methyl-3H]nisoxetine from rat hippocampus NET by filtration binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50124566((R)-2-((R)-(2-ethoxyphenoxy)(phenyl)methyl)morphol...)
Affinity DataKi:  0.690nMAssay Description:Displacement of [3H]-dopamine from rat cerebral cortex NET after 7 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM35229(3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-met...)
Affinity DataKi:  0.780nMAssay Description:Displacement of [3H]nisoxetine from rat NET in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50198230((S)-2-((S)-(2-iodophenoxy)(phenyl)methyl)morpholin...)
Affinity DataKi:  0.840nMAssay Description:Displacement of [3H]nisoxetine from NAT in Sprague-Dawley rat brain after 4 hrs by liquid scintillation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50322698(rel-1-(3,4-dichlorophenyl)-6-(methoxymethyl)-3-aza...)
Affinity DataKi:  2.51nMAssay Description:Displacement of [3H]nisoxetine from NET in rat hippocampus after 2 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]nisoxetine from rat NET in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)
Affinity DataKi:  3.90nMAssay Description:Inhibition of rat NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50297077((S)-N-(cyclobutylmethyl)-N-(pyrrolidin-3-yl)-2-(tr...)
Affinity DataKi:  3.90nMAssay Description:Binding affinity to rat NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50005548((+)-2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinol...)
Affinity DataKi:  4nMAssay Description:Inhibition of NET in rat synaptosomal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50366567(ATOMOXETINE)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50444862(CHEMBL3099493)
Affinity DataKi:  4.20nMAssay Description:Displacement of [3H]-dopamine from rat cerebral cortex NET after 7 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50330790(CHEMBL1277594 | N-Methyl-3-phenyl-3-(4-(2-(pyrroli...)
Affinity DataKi:  4.30nMAssay Description:Displacement of [3H]nisoxetine from rat NET in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM22417(3-(2-methoxyphenoxy)-N-methyl-3-phenylpropan-1-ami...)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50444861(CHEMBL3099494)
Affinity DataKi:  6.10nMAssay Description:Displacement of [3H]-dopamine from rat cerebral cortex NET after 7 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50401730(CHEMBL2206509)
Affinity DataKi:  6.30nMAssay Description:Inhibition of rat NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50254049((S)-N-methyl-4-(naphthalen-1-yl)-4-(thiophen-2-yl)...)
Affinity DataKi:  7.90nMAssay Description:Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50444860(CHEMBL3099495)
Affinity DataKi:  8.40nMAssay Description:Displacement of [3H]-dopamine from rat cerebral cortex NET after 7 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50301211((2R,3S)-2-[(2-Iodophenoxy)phenylmethyl]morpholine ...)
Affinity DataKi:  8.40nMAssay Description:Displacement of [3H]nisoxetine from NAT in Sprague-Dawley rat brain after 4 hrs by liquid scintillation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50254073((S)-4-(1H-indol-4-yl)-N-methyl-4-(thiophen-2-yl)bu...)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50190608(CHEMBL213627 | cis-(3S,6S)-(6-benzhydryl-tetrahydr...)
Affinity DataKi:  13nMAssay Description:Displacement of [3H]-dopamine from rat cerebral cortex NET after 7 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50254071((S)-3-(1H-indol-4-yl)-N-methyl-3-(thiophen-2-yl)pr...)
Affinity DataKi:  13.8nMAssay Description:Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50330791(CHEMBL1277595 | N-Methyl-4-phenyl-4-(4-(2-(pyrroli...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]nisoxetine from rat NET in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50330787(4-(3-(Methylamino)-1-phenylpropyl)-6-(2-(pyrrolidi...)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]nisoxetine from rat NET in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50136674((3R)-N-methyl-3-(1-naphthyloxy)-3-(2-thienyl)propa...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM84745(CAS_136434-34-9 | DULOXETINE | LY-248686 | LY24868...)
Affinity DataKi:  16nMAssay Description:Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50303309(3-(3,4-dichlorophenyl)-2-nortropene | CHEMBL578130)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]nisoxetine from NET in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50005548((+)-2-Methyl-4-phenyl-1,2,3,4-tetrahydro-isoquinol...)
Affinity DataKi:  20nMAssay Description:Inhibition of rat NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50190601((2S,4R,5R)-2-benzhydryl-5-[(1H-indol-5-ylmethyl)-a...)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]-dopamine from rat cerebral cortex NET after 7 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50190603(CHEMBL211077 | cis-(3S,6S)-(6-benzhydryl-tetrahydr...)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]-dopamine from rat cerebral cortex NET after 7 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM138157(US8877798, Table 3, Structure 3)
Affinity DataKi:  32nMAssay Description:Binding assay using NET, DAT and SERT enzyme.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50254111((S)-3-(3,4-dichlorophenyl)-3-(1H-indol-4-yl)-N-met...)
Affinity DataKi:  35.4nMAssay Description:Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50444871(CHEMBL3099502)
Affinity DataKi:  38nMAssay Description:Displacement of [3H]-dopamine from rat cerebral cortex NET after 7 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50048803(5-(2-(4-(benzo[d]isothiazol-3-yl)piperazin-1-yl)et...)
Affinity DataKi:  48nMAssay Description:Binding affinity to rat NETMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50254047((S)-N-methyl-3-(naphthalen-1-yl)-3-(thiophen-2-yl)...)
Affinity DataKi:  52.1nMAssay Description:Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50264064((2S,3S)-iodoreboxetine | (S)-2-((S)-(2-ethoxypheno...)
Affinity DataKi:  53.8nMAssay Description:Displacement of [3H]nisoxetine from NAT in Sprague-Dawley rat brain after 4 hrs by liquid scintillation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50264063((2R,3S)-iodoreboxetine | (R)-2-((S)-(2-ethoxypheno...)
Affinity DataKi:  58.2nMAssay Description:Displacement of [3H]nisoxetine from NAT in Sprague-Dawley rat brain after 4 hrs by liquid scintillation analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50331515(CHEMBL1708 | PAROXETINE | Paroxetine hydrochloride...)
Affinity DataKi:  59nMAssay Description:Displacement of [3H]nisoxetine from norepinephrine transporter in Sprague-Dawley rat frontal cortex after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50254072((R)-4-(1H-indol-4-yl)-N-methyl-4-(thiophen-2-yl)bu...)
Affinity DataKi:  79.7nMAssay Description:Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM138155(US8877798, Table 3, Structure 1)
Affinity DataKi:  81nMAssay Description:Binding assay using NET, DAT and SERT enzyme.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50330788(CHEMBL1277500 | N1-Methyl-N2-phenyl-N2-(4-(2-(pyrr...)
Affinity DataKi:  89nMAssay Description:Displacement of [3H]nisoxetine from rat NET in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50254027((R)-3-(3,4-dichlorophenyl)-3-(1H-indol-4-yl)-N-met...)
Affinity DataKi:  95nMAssay Description:Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM364387(US10913711, Compound 2r | US11555013, Compound 2r ...)
Affinity DataKi: >100nMAssay Description:Norepinephrine Transporter Binding Assay. Brains from male Sprague-Dawley rats weighing 200-225 g (Taconic Labs, Germantown, N.Y.) were removed, fron...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50303311(3-alpha-(4-Chlorophenyl)methoxy-3-beta-phenyl-nort...)
Affinity DataKi:  101nMAssay Description:Displacement of [3H]nisoxetine from NET in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50254050((R)-3-(1H-indol-4-yl)-N-methyl-3-(thiophen-2-yl)pr...)
Affinity DataKi:  102nMAssay Description:Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50254048((R)-N-methyl-4-(naphthalen-1-yl)-4-(thiophen-2-yl)...)
Affinity DataKi:  109nMAssay Description:Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50330789(CHEMBL1277501 | N1-Methyl-N3-phenyl-N3-(4-(2-(pyrr...)
Affinity DataKi:  110nMAssay Description:Displacement of [3H]nisoxetine from rat NET in rat cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50303307(3-(4-Chlorophenyl)-2-nortropene | CHEMBL576508)
Affinity DataKi:  120nMAssay Description:Displacement of [3H]nisoxetine from NET in rat brainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus (rat))
The Usa, As Represented By The Secretary, Dhhs

US Patent
LigandPNGBDBM50254046((R)-N-methyl-3-(naphthalen-1-yl)-3-(thiophen-2-yl)...)
Affinity DataKi:  139nMAssay Description:Displacement of [3H]nisoxetine from Sprague-dawley rat NET by liquid scintillation spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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