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Found 3 of affinity data for UniProtKB/TrEMBL: Q8WWX8
TargetSodium/myo-inositol cotransporter 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM20880((2S,3R,4R,5S,6R)-2-{4-chloro-3-[(4-ethoxyphenyl)me...)
Affinity DataIC50:  380nMAssay Description:Inhibition of SGLT6 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/myo-inositol cotransporter 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50340013(6,8-dichloro-4-((5-(4-chlorophenethyl)-4-(3,3,3-tr...)
Affinity DataIC50:  9.20E+3nMAssay Description:Inhibition of SGLT6 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium/myo-inositol cotransporter 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50340012(6,8-dichloro-4-((5-(4-chlorophenethyl)-4-propyl-4H...)
Affinity DataIC50:  1.44E+4nMAssay Description:Inhibition of SGLT6 expressed in CHO cells assessed as inhibition of [14C]-alpha-methyl-D-glucopyranoside transport after 60 mins by scintillation co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed