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Found 7 for UniProtKB: Q9BX93
TargetGroup XIIB secretory phospholipase A2-like protein(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50534272(CHEMBL4593409)
Affinity DataIC50: <14nMAssay Description:Inhibition of sPLA2 in human HepG2 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGroup XIIB secretory phospholipase A2-like protein(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50534272(CHEMBL4593409)
Affinity DataIC50:  56nMAssay Description:Inhibition of sPLA2 in atherosclerotic plaque from coronary artery disease patientMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGroup XIIB secretory phospholipase A2-like protein(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50055366((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...)
Affinity DataIC50:  114nMAssay Description:Inhibition of human recombinant sPLA2 assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGroup XIIB secretory phospholipase A2-like protein(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50055366((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...)
Affinity DataIC50:  114nMAssay Description:Inhibition of human recombinant sPLA2 assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGroup XIIB secretory phospholipase A2-like protein(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50055366((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...)
Affinity DataIC50:  131nMAssay Description:Inhibition of human recombinant sPLA2 assessed as reduction in free FA formation after 30 mins by HPLC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGroup XIIB secretory phospholipase A2-like protein(Homo sapiens)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50055366((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...)
Affinity DataIC50:  131nMAssay Description:Inhibition of human recombinant sPLA2 assessed as reduction in free FA formation after 30 mins by HPLC-MS analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50520683(CHEMBL4476621)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human sPLA2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed