BDBM7822 1,3-thiazolidine-2,4-dione::CHEMBL2071163::thiazolidinedione deriv. 21

SMILES Oc1csc(=O)[nH]1

InChI Key InChIKey=MQYUOKQDHLEQAC-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 7822   

TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM7822(1,3-thiazolidine-2,4-dione | CHEMBL2071163 | thiaz...)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetLysine-specific demethylase 4C(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM7822(1,3-thiazolidine-2,4-dione | CHEMBL2071163 | thiaz...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of KDM4C catalytic core-mediated demethylation of ARK(Me)3STGGK after 30 mins by FDH-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetLysine-specific demethylase 4C(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM7822(1,3-thiazolidine-2,4-dione | CHEMBL2071163 | thiaz...)
Affinity DataKi: >2.00E+5nMAssay Description:Inhibition of KDM4C catalytic core-mediated demethylation of ARK(Me)3STGGK after 30 mins by FDH-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed