BDBM101618 US8530652, 114

SMILES: Cc1nc2ccsc2c(n1)Nc3c4c([nH]n3)C(N(C4)C(=O)N[C@H](CN(C)C)c5ccccc5)(C)C

InChI Key: InChIKey=AYCPARAPKDAOEN-UHFFFAOYSA-N

Data: 2 KI  10 IC50  1 Kd

PDB links: 4 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 86 hits for monomerid = 101618   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase alpha-3 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	171	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.21E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-2 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.96E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D2 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C beta type (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Fyn (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Yes (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	612	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C theta type (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	568	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-1 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	543	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	407	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase Chk2 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	302	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C gamma type (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Fgr (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase N1 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	82	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase 1 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C beta type (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PAK 4 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PAK 2 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PAK 1 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PAK 2 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PAK 3 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	99	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PAK 4 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PAK 5 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PAK 6 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 7 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PAK 4 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PAK 3 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	99	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
High affinity nerve growth factor receptor (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	513	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PAK 4 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase N1 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C gamma type (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Fgr (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase N1 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
RAC-gamma serine/threonine-protein kinase (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
cGMP-dependent protein kinase 1 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.37E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase D1 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C beta type (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.49E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein kinase C beta type (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	156	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PAK 4 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PAK 4 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PAK 4 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PAK 4 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PAK 4 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PAK 4 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PAK 6 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PAK 2 (Human)	BDBM101618 (US8530652, 114) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair