BDBM10216 BI-7E7::Burnham Institute Compound 2::ethyl 2-(2,3-dihydro-1,4-benzodioxin-2-yl)-1,3-thiazole-4-carboxylate

SMILES CCOC(=O)c1csc(n1)C1COc2ccccc2O1

InChI Key InChIKey=BSHNUKBUTVBBHI-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 10216   

TargetCaspase-8(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10216(BI-7E7 | Burnham Institute Compound 2 | ethyl 2-(2...)
Affinity DataKi:  3.00E+4nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10216(BI-7E7 | Burnham Institute Compound 2 | ethyl 2-(2...)
Affinity DataIC50:  4.00E+4nMpH: 7.5 T: 2°CAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-7(Homo sapiens (Human))
Burnham Institute

LigandPNGBDBM10216(BI-7E7 | Burnham Institute Compound 2 | ethyl 2-(2...)
Affinity DataIC50:  4.60E+4nMAssay Description:Fluorescent assays were carried out in black 96-well plates. Caspase activity was monitored using a Labsystem Fluoroskan II spectrofluorometer with a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed