BDBM10458 4-AP::4-Aminopyridine 10::CHEMBL284348::DALFAMPRIDINE::pyridin-4-amine

SMILES: Nc1ccncc1

InChI Key: InChIKey=NUKYPUAOHBNCPY-UHFFFAOYSA-N

Data: 4 KI  6 IC50  1 Kd  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 10458   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetylcholinesterase (Rat)	BDBM10458 (pyridin-4-amine | CHEMBL284348 | 4-Aminopyridine 1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	7.4	37
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Carboxylic ester hydrolase (Rat)	BDBM10458 (pyridin-4-amine | CHEMBL284348 | 4-Aminopyridine 1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium channel subfamily K member 2 (Human)	BDBM10458 (pyridin-4-amine | CHEMBL284348 | 4-Aminopyridine 1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.75E+6	n/a	n/a	7.3	22
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Potassium voltage-gated channel subfamily A member 3 (Human)	BDBM10458 (pyridin-4-amine | CHEMBL284348 | 4-Aminopyridine 1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.95E+5	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM10458 (pyridin-4-amine | CHEMBL284348 | 4-Aminopyridine 1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.40E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Pteridine reductase 1 (Leishmania major)	BDBM10458 (pyridin-4-amine | CHEMBL284348 | 4-Aminopyridine 1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Human)	BDBM10458 (pyridin-4-amine | CHEMBL284348 | 4-Aminopyridine 1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.37E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily A member 1 (Human)	BDBM10458 (pyridin-4-amine | CHEMBL284348 | 4-Aminopyridine 1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
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High affinity choline transporter 1 (Mouse)	BDBM10458 (pyridin-4-amine | CHEMBL284348 | 4-Aminopyridine 1...) Show SMILES Show InChI	GoogleScholar	UniChem		4.81E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Serine protease 1 (Bovine)	BDBM10458 (pyridin-4-amine | CHEMBL284348 | 4-Aminopyridine 1...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
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Plasminogen (Human)	BDBM10458 (pyridin-4-amine | CHEMBL284348 | 4-Aminopyridine 1...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
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Prothrombin (Human)	BDBM10458 (pyridin-4-amine | CHEMBL284348 | 4-Aminopyridine 1...) Show SMILES Show InChI	GoogleScholar	UniChem		>2.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
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