BDBM10868 1,3,4-Thiadiazole-2-sulfonamide, 6::1,3,4-thiadiazole-2-sulfonamide 15::5-Amino-1,3,4-thiadiazole-2-sulphonamide (1)::5-amino-1,3,4-thiadiazole-2-sulfonamide::CHEMBL265674::aromatic/heteroaromatic sulfonamide 13

SMILES: c1(nnc(s1)S(=O)(=O)N)N

InChI Key: InChIKey=VGMVBPQOACUDRU-UHFFFAOYSA-N

Data: 151 KI  16 IC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 166 hits for monomerid = 10868   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 1 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	7.4	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Endochitinase A1 (Neosartorya fumigata)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 7 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		5.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase, alpha family (Thiomicrospira crunogena (strain XCL-2))	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Carbonic anhydrase 12 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 12 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 9 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Carbonic anhydrase 15 [19-324] (Mouse)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		48	-9.81	n/a	n/a	n/a	n/a	n/a	7.5	20
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 15 (Mouse)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		60	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		60	n/a	n/a	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Human)	BDBM10868 (1,3,4-thiadiazole-2-sulfonamide 15 | 5-amino-1,3,4...) Show SMILES Show InChI	GoogleScholar	UniChem		60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair