BDBM11242 5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide::med.21724, Compound 76::niclosamide

SMILES: c1cc(c(cc1[N+](=O)[O-])Cl)NC(=O)c2cc(ccc2O)Cl

InChI Key: InChIKey=RJMUSRYZPJIFPJ-UHFFFAOYSA-N

Data: 31 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 31 hits for monomerid = 11242   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Human)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 1 (Human)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase B-raf (Human)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ABL1 (Human)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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3-phosphoinositide-dependent protein kinase 1 (Human)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.39E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 beta (Human)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Angiopoietin-1 receptor (Human)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.78E+4	n/a	n/a	n/a	n/a	n/a	n/a
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RAC-alpha serine/threonine-protein kinase (Human)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.94E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Mast/stem cell growth factor receptor Kit (Human)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.78E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lyn (Human)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.38E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Vascular endothelial growth factor receptor 2 (Human)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 1 (Human)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.31E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Signal transducer and activator of transcription 3 (Human)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (SARS-CoV)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	7.0	25
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Mitogen-activated protein kinase 8 (Human)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK2 (Human)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Receptor-type tyrosine-protein kinase FLT3 (Human)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK2 (Human)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Protein kinase C alpha type (Human)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (2019-nCoV)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
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Signal transducer and activator of transcription 3 (Human)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.93E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Anoctamin-1 (Human)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
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Signal transducer and activator of transcription 3 (Human)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
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Replicase polyprotein 1ab (SARS-CoV)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (SARS-CoV)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (SARS-CoV)	BDBM11242 (5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenza...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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