BDBM13336 4-[4-(4-fluorophenyl)-2-(4-methanesulfinylphenyl)-1H-imidazol-5-yl]pyridine::4-[4-(4-fluorophenyl)-2-(4-methylsulfinylphenyl)-1H-imidazol-5-yl]pyridine::4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]-1H-imidazol-5-yl}pyridine::CHEMBL10::SB-203580::SB203580::cid_176155

SMILES: CS(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccc(F)cc1)-c1ccncc1

InChI Key: InChIKey=CDMGBJANTYXAIV-UHFFFAOYSA-N

Data: 3 KI  82 IC50  828 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 913 hits for monomerid = 13336   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	290	n/a	n/a	n/a	n/a	7.4	22
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Mitogen-activated protein kinase 14 (Mouse)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	20	n/a	n/a	n/a	7.0	25
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Mitogen-activated protein kinase 14 (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	48	n/a	n/a	n/a	n/a	7.5	37
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Mitogen-activated protein kinase 1 (Rat)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	7.5	37
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Mitogen-activated protein kinase 14 (Mouse)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	75	n/a	n/a	n/a	n/a	7.0	30
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Mitogen-activated protein kinase 14 [G110A] (Mouse)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	37	n/a	n/a	n/a	n/a	7.0	30
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Mitogen-activated protein kinase 14 [G110D] (Mouse)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	56	n/a	n/a	n/a	n/a	7.0	30
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Mitogen-activated protein kinase 14 (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
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Epithelial discoidin domain-containing receptor 1 (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.00E+3	n/a	n/a	n/a	7.4	25
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Discoidin domain-containing receptor 2 [A642S] (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	7.4	25
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Epidermal growth factor receptor [G719C] (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	710	n/a	n/a	n/a	7.4	25
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Ephrin type-A receptor 7 (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.20E+3	n/a	n/a	n/a	7.4	25
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Tyrosine-protein kinase FRK (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	7.4	25
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Mitogen-activated protein kinase 9 (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	130	n/a	n/a	n/a	7.4	25
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STE20-like serine/threonine-protein kinase (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 32B (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase B-raf (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase B-raf (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	530	n/a	n/a	n/a	n/a	n/a
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Citron Rho-interacting kinase (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.80E+3	n/a	n/a	n/a	n/a	n/a
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Protein-tyrosine kinase 6 (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	n/a
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RAF proto-oncogene serine/threonine-protein kinase (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	980	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase TNNI3K (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase 20 (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a
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Casein kinase I isoform delta (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a
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Casein kinase I isoform epsilon (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor [1-999,L858R] (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.90E+6	n/a	n/a	n/a	n/a	n/a
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Cyclin-G-associated kinase (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 8 (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 10 (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase kinase kinase kinase 4 (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	3.70E+3	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase NLK (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a
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Receptor-interacting serine/threonine-protein kinase 2 (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase 36 (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a
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TGF-beta receptor type-2 (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a
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TRAF2 and NCK-interacting protein kinase (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	820	n/a	n/a	n/a	n/a	n/a
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Dual specificity protein kinase TTK (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2A (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 11 (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a
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Mitogen-activated protein kinase 12 (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a
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Dual specificity mitogen-activated protein kinase kinase 2 (Human)	BDBM13336 (4-{4-(4-fluorophenyl)-2-[4-(methylsulfinyl)phenyl]...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	9.60E+3	n/a	n/a	n/a	n/a	n/a
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