BDBM14210 4-(4-(N-benzoylamino)anilino)-6-methoxy-7-(3-(1-morpholino)propoxy)-quinazoline::CHEMBL202721::N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quinazolin-4-yl}amino)phenyl]benzamide::ZM447439

SMILES: COc1cc2c(cc1OCCCN3CCOCC3)ncnc2Nc4ccc(cc4)NC(=O)c5ccccc5

InChI Key: InChIKey=OGNYUTNQZVRGMN-UHFFFAOYSA-N

Data: 22 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 42 hits for monomerid = 14210   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 1 (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity mitogen-activated protein kinase kinase 1 (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Inhibitor of nuclear factor kappa-B kinase subunit alpha (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Inhibitor of nuclear factor kappa-B kinase subunit beta (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Fibroblast growth factor receptor 1 (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Proto-oncogene tyrosine-protein kinase Src (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	880	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Lck (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ZAP-70 (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Focal adhesion kinase 1 (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity protein kinase TTK (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.28E+3	n/a	n/a	n/a	n/a
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Aurora kinase B (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Chk1 (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PLK1 (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase A (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase B (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase A (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase B (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase A (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase B-A (African clawed frog)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase B (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	156	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase B (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Aurora kinase A (Mouse)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	39	n/a	n/a	n/a	n/a	7.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase A (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase B (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase A (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase B (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase A (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase B (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase A (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase B (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase A (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase A (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	7.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase A (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	880	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase A (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aurora kinase B (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cyclin-dependent kinase 1 (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 2 (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cyclin-dependent kinase 4 (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Serine/threonine-protein kinase PLK1 (Human)	BDBM14210 (N-[4-({6-methoxy-7-[3-(morpholin-4-yl)propoxy]quin...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair