BDBM15997 2-({2-[(3-fluorophenyl)amino]pyrimidin-4-yl}amino)benzoic acid::4-anilinopyrimidine 8f

SMILES OC(=O)c1ccccc1Nc1ccnc(Nc2cccc(F)c2)n1

InChI Key InChIKey=DTMZXHDQZQLTHA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 15997   

TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15997(2-({2-[(3-fluorophenyl)amino]pyrimidin-4-yl}amino)...)
Affinity DataIC50:  28nMAssay Description:In vitro substrate phosphorylation using purified recombinant JNK, was incubated with substrate, and test compounds in the presence of 5uM ATP/ [gamm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15997(2-({2-[(3-fluorophenyl)amino]pyrimidin-4-yl}amino)...)
Affinity DataIC50:  28nMAssay Description:Inhibition of JNK1 expressed in Escherichia coli or baculovirus-infected insect cells by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15997(2-({2-[(3-fluorophenyl)amino]pyrimidin-4-yl}amino)...)
Affinity DataIC50:  50nMAssay Description:Inhibition of JNK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM15997(2-({2-[(3-fluorophenyl)amino]pyrimidin-4-yl}amino)...)
Affinity DataIC50:  28nMAssay Description:Inhibition of JNK1alpha1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed