BindingDB PrimarySearch

BDBM17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US11786535, Compound Indomethacin::US9271961, Indomethacin::indometacin

SMILES: Cc1c(c2cc(ccc2n1C(=O)c3ccc(cc3)Cl)OC)CC(=O)O

InChI Key: InChIKey=CGIGDMFJXJATDK-UHFFFAOYSA-N

Data: 61 KI 437 IC50 5 Kd 3 EC50

PDB links: 24 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 517 hits for monomerid = 17638
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Prostaglandin G/H synthase 1 (Sheep)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	50	n/a	n/a	n/a	n/a	8.0	37
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	37
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mouse)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	37
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 [582-599] (Human)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Sheep)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	210	n/a	n/a	n/a	n/a	8.0	37
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.24E+3	n/a	n/a	n/a	n/a	8.0	37
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Sheep)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	600	n/a	n/a	n/a	n/a	8.0	25
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.85E+4	n/a	n/a	n/a	n/a	8.0	25
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Sheep)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	220	n/a	n/a	n/a	n/a	8.0	25
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.44E+3	n/a	n/a	n/a	n/a	8.0	25
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Sheep)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Sheep)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Sheep)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mouse)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mouse)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Sheep)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [18-504,V335L] (Mouse)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [18-604,V509I] (Mouse)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [18-604,S516A] (Mouse)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [18-604,R106Q] (Mouse)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	300	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 [18-604,Y541F] (Mouse)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Human)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	72.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Human)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	72.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4.93E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Albumin (Human)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Phospholipase A2, major isoenzyme (Pig)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (Bovine)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 4 (Human)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Bile salt export pump (Human)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 3 (Human)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	6.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Sheep)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (Rat)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (Rat)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Human)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Cytochrome c oxidase subunit 2 (Human)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Sheep)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.63E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Human)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (Rat)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Thromboxane-A synthase (Human)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Sheep)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM17638 (indometacin \| Indocin \| 2-{1-[(4-chlorophenyl)carb...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	960	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair

Displayed 1 to 50 (of 517 total ) | Next | Last >>