BDBM17638 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid::CHEMBL6::Indocin::Indomethacin::US11478464, Compound Indomethacin::US11786535, Compound Indomethacin::US9271961, Indomethacin::indometacin

SMILES COc1ccc2n(C(=O)c3ccc(Cl)cc3)c(C)c(CC(O)=O)c2c1

InChI Key InChIKey=CGIGDMFJXJATDK-UHFFFAOYSA-N

Data  61 KI  428 IC50  5 Kd  3 EC50

PDB links: 24 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 17638   

TargetDehydrogenase/reductase SDR family member 9(Homo sapiens (Human))
Institute For Natural Product Research And Infection Biology

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of 3alphaHSDMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Institute For Natural Product Research And Infection Biology

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of COX1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute For Natural Product Research And Infection Biology

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  7.71E+4nMAssay Description:Inhibition of COX2More data for this Ligand-Target Pair