BDBM19 (2S,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-{[(2R,3S,4R,5S)-5-{[(1R,2R,3S,5R,6S)-3,5-diamino-2-{[(2R,3R,4R,5S,6R)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy}-6-hydroxycyclohexyl]oxy}-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl]oxy}oxane-3,4-diol::KDR Kinase Inhibitor, 3::Neomycin::Neomycin B

SMILES: NC[C@@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@@H](O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3O[C@H]3O[C@H](CN)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O)[C@H](N)[C@@H](O)[C@@H]1O

InChI Key: InChIKey=PGBHMTALBVVCIT-UHFFFAOYSA-N

Data: 5 KI  3 IC50  2 Kd  9 ITC

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 19   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine--tRNA ligase (Thermus thermophilus)	BDBM19 (KDR Kinase Inhibitor, 3 | Neomycin | (2S,3S,4R,5R,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5	n/a	n/a	n/a	7.5	0
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Vascular endothelial growth factor receptor 2 (Human)	BDBM19 (KDR Kinase Inhibitor, 3 | Neomycin | (2S,3S,4R,5R,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
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Protein Rev (Human immunodeficiency virus type 1)	BDBM19 (KDR Kinase Inhibitor, 3 | Neomycin | (2S,3S,4R,5R,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a
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Lecithin retinol acyltransferase (Human)	BDBM19 (KDR Kinase Inhibitor, 3 | Neomycin | (2S,3S,4R,5R,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.49E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM19 (KDR Kinase Inhibitor, 3 | Neomycin | (2S,3S,4R,5R,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.35E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Lethal factor (Bacillus anthracis)	BDBM19 (KDR Kinase Inhibitor, 3 | Neomycin | (2S,3S,4R,5R,...) Show SMILES Show InChI	GoogleScholar	UniChem		7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Lethal factor (Bacillus anthracis)	BDBM19 (KDR Kinase Inhibitor, 3 | Neomycin | (2S,3S,4R,5R,...) Show SMILES Show InChI	GoogleScholar	UniChem		500	-8.59	n/a	n/a	n/a	n/a	n/a	n/a	25
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Lethal factor (Bacillus anthracis)	BDBM19 (KDR Kinase Inhibitor, 3 | Neomycin | (2S,3S,4R,5R,...) Show SMILES Show InChI	GoogleScholar	UniChem		500	-8.50	n/a	n/a	n/a	n/a	n/a	7.4	22
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1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-4 (Rat)	BDBM19 (KDR Kinase Inhibitor, 3 | Neomycin | (2S,3S,4R,5R,...) Show SMILES Show InChI	GoogleScholar	UniChem		5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (Rat)	BDBM19 (KDR Kinase Inhibitor, 3 | Neomycin | (2S,3S,4R,5R,...) Show SMILES Show InChI	GoogleScholar	UniChem		5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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