BDBM19441 2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethoxy]phenyl}carbonyl)-1-benzothiophen-6-ol::CHEMBL81::Evista::Keoxifene::RALOXIFENE HYDROCHLORIDE::Raloxifene::Raloxifene (7)::Raloxifene, 6::[6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone::cid_11071264

SMILES: Oc1ccc(cc1)-c1sc2cc(O)ccc2c1C(=O)c1ccc(OCCN2CCCCC2)cc1

InChI Key: InChIKey=GZUITABIAKMVPG-UHFFFAOYSA-N

Data: 28 KI  99 IC50  2 Kd  11 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 135 hits for monomerid = 19441   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20.6	n/a	n/a	n/a	n/a	7.5	22
TBA									Citation and Details
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Estrogen receptor beta (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	557	n/a	n/a	n/a	n/a	7.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	2.40	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	260	n/a	341	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	2.40	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	260	n/a	341	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	22	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	260	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phospholipase D1 (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phospholipase D1 (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a	n/a	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phospholipase D1 (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phospholipase D1 (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8.50E+3	n/a	n/a	n/a	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phospholipase D1 (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.00E+4	n/a	n/a	n/a	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ubiquitin-conjugating enzyme E2 N (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Ubiquitin-conjugating enzyme E2 N (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bcl-2-related protein A1 (Mouse)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phospholipase D1 (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phospholipase D2 (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phospholipase D (Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22...)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
HLA class I histocompatibility antigen, A alpha chain (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.20E+4	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Rat)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aldehyde oxidase (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aldehyde oxidase 1 (Rabbit)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.53E+6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.660	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.180	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Complement C5 (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.720	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Rat)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Rat)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Rat)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Rat)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM19441 (Evista | CHEMBL81 | Keoxifene | Raloxifene, 6 | RA...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair