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Found 9 Enz. Inhib. hit(s) with Target = 'Aldehyde oxidase' and Ligand = 'BDBM19441'
TargetAldehyde oxidase(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataKi:  0.870nMAssay Description:Uncompetitive inhibition of human liver cytosolic aldehyde oxidase using phthalazine as substrate assessed as enzyme-substrate complex by Lineweaver-...More data for this Ligand-Target Pair
TargetAldehyde oxidase(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataKi:  0.870nMAssay Description:Uncompetitive type inhibition of human AOX assessed as inhibition constant using phthalazine as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
TargetAldehyde oxidase(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataKi:  0.870nMAssay Description:Uncompetitive type inhibition of human AOX assessed as inhibition constant using vanillin as substrate by HPLC-MS analysisMore data for this Ligand-Target Pair
TargetAldehyde oxidase(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataKi:  0.870nMAssay Description:Uncompetitive type inhibition of human AOX assessed as inhibition constant using nicotine-1(S)-iminium ion as substrate incubated for 2 mins by HPLC-...More data for this Ligand-Target Pair
TargetAldehyde oxidase(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataKi:  2.30nMAssay Description:Competitive inhibition of human liver cytosolic aldehyde oxidase using DACA as substrate assessed as free enzyme by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
TargetAldehyde oxidase(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human aldehyde oxidaseMore data for this Ligand-Target Pair
TargetAldehyde oxidase(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human aldehyde oxidaseMore data for this Ligand-Target Pair
TargetAldehyde oxidase(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of human AOX using phthalazine as substrate preincubated for 30 mins followed by substrate addition by HPLC-MS analysisMore data for this Ligand-Target Pair
TargetAldehyde oxidase(Homo sapiens (Human))
Washington State University

Curated by ChEMBL
LigandPNGBDBM19441(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)
Affinity DataIC50:  8nMAssay Description:Inhibition of Homo sapiens (human) aldehyde oxidaseMore data for this Ligand-Target Pair