BDBM21886 2,9-disubstituted 6-oxopurine, 12j::9-[4-(3,5-dimethylpiperazin-1-yl)butyl]-2-(phenylamino)-6,9-dihydro-3H-purin-6-one dihydrochloride

SMILES CC1CN(CCCCn2cnc3c2nc(Nc2ccccc2)[nH]c3=O)CC(C)N1

InChI Key InChIKey=SIEXHGADVYZANN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 21886   

TargetThymidine kinase(Human herpesvirus 2)
Glsynthesis

LigandPNGBDBM21886(2,9-disubstituted 6-oxopurine, 12j | 9-[4-(3,5-dim...)
Affinity DataIC50:  800nMAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1)
Glsynthesis

LigandPNGBDBM21886(2,9-disubstituted 6-oxopurine, 12j | 9-[4-(3,5-dim...)
Affinity DataIC50:  7.10E+3nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed