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BDBM22955 4-methoxyphenyl 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetate::CHEMBL316866::Indomethacin derivative, 8
SMILES: COc1ccc(OC(=O)Cc2c(C)n(C(=O)c3ccc(Cl)cc3)c3ccc(OC)cc23)cc1
InChI Key: InChIKey=RZUDCMGEWDZMRH-UHFFFAOYSA-N
Data: 5 IC50
| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Prostaglandin G/H synthase 1 (Sheep) | BDBM22955![]() (CHEMBL316866 | 4-methoxyphenyl 2-{1-[(4-chlorophen...) | GoogleScholar | UniChem | n/a | n/a | >6.60E+4 | n/a | n/a | n/a | n/a | 8.0 | 37 | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prostaglandin G/H synthase 2 (Human) | BDBM22955![]() (CHEMBL316866 | 4-methoxyphenyl 2-{1-[(4-chlorophen...) | GoogleScholar | UniChem | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | 37 | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prostaglandin G/H synthase 2 (Mouse) | BDBM22955![]() (CHEMBL316866 | 4-methoxyphenyl 2-{1-[(4-chlorophen...) | GoogleScholar | UniChem | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | 37 | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prostaglandin G/H synthase 1 (Sheep) | BDBM22955![]() (CHEMBL316866 | 4-methoxyphenyl 2-{1-[(4-chlorophen...) | GoogleScholar | UniChem | n/a | n/a | >6.60E+4 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Prostaglandin G/H synthase 2 (Human) | BDBM22955![]() (CHEMBL316866 | 4-methoxyphenyl 2-{1-[(4-chlorophen...) | GoogleScholar | UniChem | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||