BDBM22971 2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid::CHEMBL509::Meclofenamate::Meclofenamic acid::US11337935, Compound Meclofenamic-acid::US20240002326, Compound Meclofenamic acid

SMILES: Cc1ccc(c(c1Cl)Nc2ccccc2C(=O)O)Cl

InChI Key: InChIKey=SBDNJUWAMKYJOX-UHFFFAOYSA-N

Data: 6 KI  37 IC50  2 Kd  2 EC50

PDB links: 5 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 48 hits for monomerid = 22971   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldo-keto reductase family 1 member C2 (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
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DNA oxidative demethylase ALKBH2 (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 1 (Sheep)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	8.0	37
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RNA demethylase ALKBH5 (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-ketoglutarate-dependent dioxygenase FTO (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.74E+4	n/a	n/a	n/a	n/a	n/a	n/a
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N6-adenosine-methyltransferase catalytic subunit (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 1/2 (Rat)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 1/2 (Rat)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
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Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aldo-keto reductase family 1 member C4 (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Aldo-keto reductase family 1 member C1 (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Aldo-keto reductase family 1 member C3 (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member C4 (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member C3 (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member C2 (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member C1 (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Transthyretin (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-ketoglutarate-dependent dioxygenase FTO (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Prostaglandin G/H synthase 2 (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	37
TBA									Citation and Details
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Prostaglandin G/H synthase 2 (Mouse)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	37
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Transcription factor SOX-18 (Mouse)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.63E+5	n/a	n/a	n/a	n/a	7.5	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transthyretin (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	504	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transcription factor SOX-18 (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.63E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Bile salt export pump (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.72E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member C1 (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Aldo-keto reductase family 1 member C3 (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	512	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Polyunsaturated fatty acid 5-lipoxygenase (Rat)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1/2 (Rat)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 1 (Sheep)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mouse)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Prostaglandin G/H synthase 2 (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
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Prostaglandin G/H synthase 2 (Mouse)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
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Replicase polyprotein 1a (SARS-CoV)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.20E+5	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 4 group A member 1 (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a
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Platelet-derived growth factor receptor alpha/beta (Mouse)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	900	n/a	n/a	n/a	n/a
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Alpha-ketoglutarate-dependent dioxygenase FTO (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Fatty acid-binding protein, liver (Rat)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		256	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Fatty acid-binding protein, liver (Rat)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		379	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Fatty acid-binding protein, intestinal (Human)	BDBM22971 (Meclofenamate | CHEMBL509 | 2-[(2,6-dichloro-3-met...) Show SMILES Show InChI	GoogleScholar	UniChem		8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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