Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with Target = 'Prostaglandin G/H synthase 2' and Ligand = 'BDBM22971'
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
St. Bartholomew'S and The Royal London School of Medicine and Dentistry

Curated by PDSP Ki Database
LigandPNGBDBM22971(2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid...)
Affinity DataKi:  200nMMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
St. Bartholomew'S and The Royal London School of Medicine and Dentistry

Curated by PDSP Ki Database
LigandPNGBDBM22971(2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid...)
Affinity DataKi:  700nMMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
St. Bartholomew'S and The Royal London School of Medicine and Dentistry

Curated by PDSP Ki Database
LigandPNGBDBM22971(2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid...)
Affinity DataIC50:  40nMAssay Description:Inhibition of the human Prostaglandin G/H synthase 2 was determined by thin-layer chromatography assayMore data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
St. Bartholomew'S and The Royal London School of Medicine and Dentistry

Curated by PDSP Ki Database
LigandPNGBDBM22971(2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid...)
Affinity DataIC50:  50nMT: 2°CAssay Description:For the time-dependent inhibition studies, COX enzyme was incubated with test compounds for 20 min and then analyzed for remaining COX activity by tr...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School of Medicine

LigandPNGBDBM22971(2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid...)
Affinity DataIC50:  130nMT: 2°CAssay Description:Inhibition assays in triplicate were performed by preincubating enzyme (60-80 nM) and inhibitors (0-5 mM) for 20 min at 25°C followed by the add...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School of Medicine

LigandPNGBDBM22971(2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid...)
Affinity DataIC50:  200nMAssay Description:Inhibition of the murine wild type Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Mus musculus (Mouse))
Vanderbilt University School of Medicine

LigandPNGBDBM22971(2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid...)
Affinity DataIC50:  400nMAssay Description:Inhibition of the murine Arg120Ala mutant type COX-2More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
St. Bartholomew'S and The Royal London School of Medicine and Dentistry

Curated by PDSP Ki Database
LigandPNGBDBM22971(2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid...)
Affinity DataIC50:  700nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair