BDBM237182 Ceftizoxime
SMILES CO\N=C(/C(=O)N[C@H]1[C@H]2SCC=C(N2C1=O)C(O)=O)c1csc(N)n1
InChI Key InChIKey=NNULBSISHYWZJU-LLKWHZGFSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 237182
Affinity DataKi: 2.28E+4nM IC50: 3.97E+4nMpH: 8.0Assay Description:Enzymatic activity was measured by Beutler's method with a Shimadzu Spectrophotometer UV-(1208), at 25°C. The assay system contained 100 mM Tris-...More data for this Ligand-Target Pair
Affinity DataKi: 5.18E+4nM ΔG°: -5.84kcal/mole IC50: 7.91E+4nMpH: 7.4 T: 2°CAssay Description:CA activity was assayed according to method of Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] described previously by Innocenti e...More data for this Ligand-Target Pair
Affinity DataKi: 8.61E+4nM ΔG°: -5.54kcal/mole IC50: 7.94E+4nMpH: 7.4 T: 2°CAssay Description:CA activity was assayed according to method of Verpoorte et al. [Verpoorte et al., J. Biol. Chem., 242:4221-4229] described previously by Innocenti e...More data for this Ligand-Target Pair
Affinity DataKi: 1.21E+5nM IC50: 1.86E+5nMpH: 7.0Assay Description:Glutathione peroxidase was assayed in a l-ml system containing 0.1 M potassium phosphate buffer, pH 7.0, 0.2 mM NADPH, 1 i.u. glutathione reductase, ...More data for this Ligand-Target Pair
Affinity DataKi: 1.65E+5nM IC50: 2.78E+5nMpH: 6.5Assay Description:Enzymatic activity was determined spectrophotometrically by measuring the conjugation of CDNB with GSH. The 1 ml assay mixture contained 0.5 mM CDNB,...More data for this Ligand-Target Pair