BDBM26673 6-(5-bromo-2-hydroxyphenyl)-2-oxo-4-phenyl-1,2-dihydropyridine-3-carbonitrile::CHEMBL391586::pyridone-based compound, 1

SMILES: c1ccc(cc1)C2=C(C(=O)NC(=C2)c3cc(ccc3O)Br)C#N

InChI Key: InChIKey=SVSYJTYGPLVUOZ-UHFFFAOYSA-N

Data: 4 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 26673   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Human)	BDBM26673 (CHEMBL391586 | 6-(5-bromo-2-hydroxyphenyl)-2-oxo-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	7.5	23
TBA									Citation and Details
					More data for this Ligand-Target Pair
Baculoviral IAP repeat-containing protein 5 (Human)	BDBM26673 (CHEMBL391586 | 6-(5-bromo-2-hydroxyphenyl)-2-oxo-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Human)	BDBM26673 (CHEMBL391586 | 6-(5-bromo-2-hydroxyphenyl)-2-oxo-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Human)	BDBM26673 (CHEMBL391586 | 6-(5-bromo-2-hydroxyphenyl)-2-oxo-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Baculoviral IAP repeat-containing protein 5 (Human)	BDBM26673 (CHEMBL391586 | 6-(5-bromo-2-hydroxyphenyl)-2-oxo-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	5.70E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Serine/threonine-protein kinase pim-1 (Human)	BDBM26673 (CHEMBL391586 | 6-(5-bromo-2-hydroxyphenyl)-2-oxo-4...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair