BindingDB PrimarySearch

BDBM30707 2-(5-methoxy-1H-indol-3-yl)-N,N-dimethyl-ethanamine::2-(5-methoxy-1H-indol-3-yl)-N,N-dimethylethanamine::2-(5-methoxy-1H-indol-3-yl)ethyl-dimethyl-amine::3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE::CHEMBL7257::MLS000069438::Methoxydimethyltryptamines::SMR000059066::US20240166618, Compound 5-MeO-DMT::US20240246911, Compound 5-MeO-DMT::US20240317683, Compound 5-MeO-DMT::WO2023019367, Compound 5-MeO-DMT::cid_1832

SMILES: CN(C)CCc1c[nH]c2c1cc(cc2)OC

InChI Key: InChIKey=ZSTKHSQDNIGFLM-UHFFFAOYSA-N

Data: 55 KI 15 IC50 1 Kd 12 EC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 125 hits for monomerid = 30707
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 1A (Human)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	1.06E+3	n/a	n/a	7.4	23
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5-hydroxytryptamine receptor 1A (Human)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	197	n/a	n/a	7.4	23
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5-hydroxytryptamine receptor 1E (Human)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	92	n/a	n/a	7.4	23
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Sphingosine 1-phosphate receptor 3 (Human)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	<1.00E+4	n/a	n/a	n/a	n/a
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Sodium-dependent serotonin transporter (Human)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	7.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
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TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	<2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	<500	n/a	n/a	n/a	n/a	n/a	n/a
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TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Human)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rat)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
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TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Human)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rat)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rat)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
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TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rat)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
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TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Human)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
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TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Guinea pig)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
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TBA				More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rat)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rat)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
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TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	1.80	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	1.80	n/a	n/a	n/a	n/a
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TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	9.5	n/a	n/a	n/a	n/a	n/a	n/a
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TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	462	n/a	n/a	n/a	n/a
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5-hydroxytryptamine receptor 2B (Rat)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a
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TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Rat)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	78	n/a	n/a	n/a	n/a
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TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Rat)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	83.2	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Electric eel)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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TBA				More data for this Ligand-Target Pair
Melatonin receptor type 1A (Human)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	257	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Melatonin receptor type 1B (Human)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	112	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Human)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Human)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Dog)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	5.12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rat)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Human)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rat)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	7.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rat)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	8.26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rat)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	8.31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rat)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rat)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Human)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Guinea pig)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	13.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rat)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rat)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Serotonin 2 (5-HT2) receptor (Rat)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Human)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Human)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Human)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
Melatonin receptor type 1B (Human)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA								Citation and Details
TBA				More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Human)	BDBM30707 (3-(2-DIMETHYLAMINOETHYL)-5-METHOXYINDOLE \| CHEMBL7...) Show SMILES Show InChI	GoogleScholar	UniChem	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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TBA				More data for this Ligand-Target Pair

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