BDBM32102 1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7(1H,6H)-dione::1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7-dione::1,6-dimethylpyrimido[5,4-e][1,2,4]triazine-5,7-quinone::MLS000087831::SMR000024051::US9284299, PKF118-310::US9738628, Compound PKF118-310::cid_66541

SMILES: Cn1ncnc2c1nc(=O)n(C)c2=O

InChI Key: InChIKey=SLGRAIAQIAUZAQ-UHFFFAOYSA-N

Data: 14 KI  49 IC50  6 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 69 hits for monomerid = 32102   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 7 (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cathepsin B (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	46.1	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Procathepsin L (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	226	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin S (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	176	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Procathepsin L (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Dual specificity protein phosphatase 3 (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 3 (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	980	n/a	n/a	n/a	n/a	n/a	n/a
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Photoreceptor-specific nuclear receptor (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.98E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Isoform 2 of Nuclear receptor corepressor 2 (TRAC-1) (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.98E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6.27E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein RecA (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	90.2	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein RecA (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	<18	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 22 (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein phosphatase non-receptor type 22 (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 6 (Rat)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein RecA (Mycobacterium tuberculosis (strain ATCC 25618 / H3...)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	323	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transcription factor 4 (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	541	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4A (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4A (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transcription factor 4 (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Catenin beta-1 (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Catenin beta-1 (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Catenin beta-1 (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	870	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-2 (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2) (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	920	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 1 (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	743	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 1 (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 1 (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 6 (Rat)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Sphingosine 1-phosphate receptor 1 (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.73E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cathepsin B (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	47.3	n/a	n/a	n/a	n/a	6.8	23
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 1 (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	184	n/a	n/a	n/a	n/a	7.0	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Heat shock protein HSP 90-alpha (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	238	n/a	n/a	n/a	n/a	7.4	23
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 6 (Rat)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Dual specificity protein phosphatase 6 (Rat)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	535	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	349	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Steroidogenic factor 1 (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2) (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	690	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Steroidogenic factor 1 (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	633	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	551	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
M-phase inducer phosphatase 2 (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Heat shock protein HSP 90-alpha (Human)	BDBM32102 (cid_66541 | 1,6-dimethylpyrimido[5,4-e][1,2,4]tria...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.88E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair