BDBM32287 (5E)-5-[[5-(2-chlorophenyl)-2-furanyl]methylidene]-3-(2-oxolanylmethyl)-2-sulfanylidene-4-thiazolidinone::(5E)-5-[[5-(2-chlorophenyl)-2-furyl]methylene]-3-(tetrahydrofurfuryl)-2-thioxo-thiazolidin-4-one::(5E)-5-[[5-(2-chlorophenyl)furan-2-yl]methylidene]-3-(oxolan-2-ylmethyl)-2-sulfanylidene-1,3-thiazolidin-4-one::5-[5-(2-Chloro-phenyl)-furan-2-ylmethylene]-3-(tetrahydro-furan-2-ylmethyl)-2-thioxo-thiazolidin-4-one::MLS000568719::SMR000175743::cid_5759067

SMILES Clc1ccccc1-c1ccc(\C=C2\SC(=S)N(CC3CCCO3)C2=O)o1

InChI Key InChIKey=CELQNOCWABHQCF-LICLKQGHSA-N

Data  2 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 32287   

TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32287((5E)-5-[[5-(2-chlorophenyl)-2-furanyl]methylidene]...)
Affinity DataEC50:  1.55E+3nMpH: 7.4 T: 2°CAssay Description:The HTS assay was conducted in 384-well microplates in a total assay volume per well of 10.1 microliters (5 microliters of bead mixture, 0.1 microlit...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBcl-2-related protein A1(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32287((5E)-5-[[5-(2-chlorophenyl)-2-furanyl]methylidene]...)
Affinity DataEC50:  2.60E+3nMpH: 7.4 T: 2°CAssay Description:The multiplex is constructed by using beads for each protein target that have been labeled with varying intensities of red color, so that each assay ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetApoptosis regulator Bcl-2(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32287((5E)-5-[[5-(2-chlorophenyl)-2-furanyl]methylidene]...)
Affinity DataEC50:  2.33E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetGlutathione S-transferase Mu 1(Homo sapiens (Human))
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM32287((5E)-5-[[5-(2-chlorophenyl)-2-furanyl]methylidene]...)
Affinity DataEC50:  1.73E+4nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-re...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEphrin type-A receptor 4(Mus musculus)
Sanford-Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM32287((5E)-5-[[5-(2-chlorophenyl)-2-furanyl]methylidene]...)
Affinity DataIC50:  400nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetEphrin type-A receptor 4(Mus musculus)
Sanford-Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM32287((5E)-5-[[5-(2-chlorophenyl)-2-furanyl]methylidene]...)
Affinity DataIC50: >5.00E+4nMAssay Description:Sanford-Burnham Center for Chemical Genomics (SBCCG) Sanford-Burnham Medical Research Institute (SBMRI, San Diego, CA) NIH Molecular Libraries Screen...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
LigandPNGBDBM32287((5E)-5-[[5-(2-chlorophenyl)-2-furanyl]methylidene]...)
Affinity DataEC50:  2.14E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay