BDBM32370 adenosine-derived inhibitor (Grp78), 2::adenosine-derived inhibitor, 4

SMILES: Nc1nc2c(N)ncnc2n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O

InChI Key: InChIKey=DVGWFQILDUEEGX-UHFFFAOYSA-N

Data: 3 KI  1 IC50  5 Kd  1 K_off  1 ITC

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 32370   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heat shock 70 kDa protein 1A (Human)	BDBM32370 (adenosine-derived inhibitor (Grp78), 2 | adenosine...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.40E+3	n/a	n/a	n/a	n/a	7.4	23
TBA									Citation and Details
					More data for this Ligand-Target Pair
Heat shock 70 kDa protein 1A (Human)	BDBM32370 (adenosine-derived inhibitor (Grp78), 2 | adenosine...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.10E+4	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
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Endoplasmic reticulum chaperone BiP (Human)	BDBM32370 (adenosine-derived inhibitor (Grp78), 2 | adenosine...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6.80E+3	n/a	>1	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Heat shock 70 kDa protein 1A (Human)	BDBM32370 (adenosine-derived inhibitor (Grp78), 2 | adenosine...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	1.10E+4	n/a	n/a	n/a	7.4	25
TBA									Citation and Details
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Heat shock cognate 71 kDa protein (Human)	BDBM32370 (adenosine-derived inhibitor (Grp78), 2 | adenosine...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6.92E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Heat shock cognate 71 kDa protein (Human)	BDBM32370 (adenosine-derived inhibitor (Grp78), 2 | adenosine...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Heat shock 70 kDa protein 1A (Human)	BDBM32370 (adenosine-derived inhibitor (Grp78), 2 | adenosine...) Show SMILES Show InChI	GoogleScholar	UniChem		4.46E+3	-7.29	n/a	n/a	n/a	n/a	n/a	7.4	25
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Adenosine receptor A2a (Rat)	BDBM32370 (adenosine-derived inhibitor (Grp78), 2 | adenosine...) Show SMILES Show InChI	GoogleScholar	UniChem		2.41E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Adenosine deaminase (Bovine)	BDBM32370 (adenosine-derived inhibitor (Grp78), 2 | adenosine...) Show SMILES Show InChI	GoogleScholar	UniChem		8.95E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 32370

Cell (A)	Syringe (B)	Cell Links	Syringe Links	Cell + Syr Links	ΔG° kcal/mole	-TΔS° kcal/mole	ΔH° kcal/mole	log K	pH	Temp °C
Grp78 (Human)	BDBM32370 (adenosine-derived inhibitor (Grp78), 2 | adenosine...)	GoogleScholar			n/a	-1.57	-13.2	4.15	7.40	25
TBA					Details of this binding reaction