BDBM32370 adenosine-derived inhibitor (Grp78), 2::adenosine-derived inhibitor, 4
SMILES Nc1nc2c(N)ncnc2n1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O
InChI Key InChIKey=DVGWFQILDUEEGX-UUOKFMHZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 32370
Affinity DataKi: 4.46E+3nM ΔG°: -7.29kcal/molepH: 7.4 T: 2°CAssay Description:The assay was based on the fluorescence polarization of the unbound small binding partner will be low, and its binding to a larger binding partner wi...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Rattus norvegicus (rat))
National Institute Of Diabetes
Curated by ChEMBL
National Institute Of Diabetes
Curated by ChEMBL
Affinity DataKi: 2.41E+4nMAssay Description:Binding affinity to adenosine A2A receptor in rat striatal membranes by measuring displacement of specific [3H]-CGS- 21680 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 8.95E+4nMAssay Description:Inhibition of calf placental adenosine deaminase by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 1 hit for monomerid = 32370
ITC Data−TΔS°: -1.57kcal/mole ΔH°: -13.2kcal/mole logk: 1.41E+4
pH: 7.4 T: 25.00°C
pH: 7.4 T: 25.00°C