BindingDB PrimarySearch_ki

Search and Browse
- Target
- Compound
- Special tools
- Citation
- Special Data Sets
- Other Databases
  - PDB 85% 100% Seq ID
  - UniProtKB/Swiss-Prot
  - UniProtKB/TrEMBL
  - PubMed
Download
- All Compounds & Data
- Target Names &
  - Ki IC50 Kd EC50
  - ΔG° ΔH° -TΔS°
Enter Data

BDBM32387 phenyl-substituted sulfonamides, 6d

SMILES: c1ccc(cc1)CN(CCNCCN(Cc2ccccc2)S(=O)(=O)c3ccc(cc3)N)S(=O)(=O)c4ccc(cc4)N

InChI Key: InChIKey=LGNWJMPLPCSVBL-UHFFFAOYSA-N

Data: 4 KI 2 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 32387
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Renin (Human)	BDBM32387 (phenyl-substituted sulfonamides, 6d) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Beta-secretase 1 [22-457] (Human)	BDBM32387 (phenyl-substituted sulfonamides, 6d) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>2.50E+5	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Pepsin A (Pig)	BDBM32387 (phenyl-substituted sulfonamides, 6d) Show SMILES Show InChI	GoogleScholar	UniChem		3.90E+3	-7.37	n/a	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Plasmepsin II (Plasmodium falciparum)	BDBM32387 (phenyl-substituted sulfonamides, 6d) Show SMILES Show InChI	GoogleScholar	UniChem		4.20E+3	-7.28	n/a	n/a	n/a	n/a	n/a	4.5	23
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Plasmepsin IV (Plasmodium falciparum (isolate 3D7))	BDBM32387 (phenyl-substituted sulfonamides, 6d) Show SMILES Show InChI	GoogleScholar	UniChem		7.50E+3	-6.94	n/a	n/a	n/a	n/a	n/a	4.5	23
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Dimer of Gag-Pol polyprotein [501-599] (Human immunodeficiency virus type 1)	BDBM32387 (phenyl-substituted sulfonamides, 6d) Show SMILES Show InChI	GoogleScholar	UniChem		9.60E+3	-6.79	n/a	n/a	n/a	n/a	n/a	5.5	23
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair