BDBM33577 3-(1,3-benzothiazol-2-yl)phenol::MLS000063319::SMR000074978::cid_242605

SMILES Oc1cccc(c1)-c1nc2ccccc2s1

InChI Key InChIKey=JIWVTDBBMGSTFI-UHFFFAOYSA-N

Data  5 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 33577   

TargetProthrombin(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM33577(3-(1,3-benzothiazol-2-yl)phenol | MLS000063319 | S...)
Affinity DataIC50: >5.00E+4nMpH: 7.5 T: 2°CAssay Description:HTS was performed using 217,350 compounds of the MLSCN library individually plated into 10ul 1536 compound plates at a concentration of 2.5 mM each, ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetMatrix metalloproteinase-14 [1-36](Homo sapiens (Human))
Sanford-Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM33577(3-(1,3-benzothiazol-2-yl)phenol | MLS000063319 | S...)
Affinity DataEC50:  2.99E+3nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetTranscription factor p65(Homo sapiens (Human))
Srmlsc

Curated by PubChem BioAssay
LigandPNGBDBM33577(3-(1,3-benzothiazol-2-yl)phenol | MLS000063319 | S...)
Affinity DataEC50:  4.10E+3nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBeta-glucuronidase(Bos taurus (Bovine))
University Of Karachi

Curated by ChEMBL
LigandPNGBDBM33577(3-(1,3-benzothiazol-2-yl)phenol | MLS000063319 | S...)
Affinity DataIC50:  3.61E+4nMAssay Description:Inhibition of bovine liver beta glucuronidase assessed as p-nitrophenol formation after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxysterols receptor LXR-beta(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM33577(3-(1,3-benzothiazol-2-yl)phenol | MLS000063319 | S...)
Affinity DataIC50:  6.76E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNuclear hormone receptor family member daf-12(Caenorhabditis elegans)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM33577(3-(1,3-benzothiazol-2-yl)phenol | MLS000063319 | S...)
Affinity DataIC50:  6.76E+4nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: UT Southwestern Assay Provider: David Mangelsdorf,...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetKallikrein-5(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM33577(3-(1,3-benzothiazol-2-yl)phenol | MLS000063319 | S...)
Affinity DataIC50:  5.00E+4nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay